Functional near-infrared spectroscopy in non-invasive neuromodulation  

作　　者：Congcong Huo Gongcheng Xu Hui Xie Tiandi Chen Guangjian Shao Jue Wang Wenhao Li Daifa Wang Zengyong Li 

机构地区：[1]Beijing Advanced Innovation Center for Biomedical Engineering,Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education,School of Biological Science and Medical Engineering,Beihang University,Beijing,China [2]Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability,National Research Center for Rehabilitation Technical Aids,Beijing,China [3]School of Mechatronic Engineering and Automation,Foshan University,Foshan,Guangdong Province,China [4]School of Rehabilitation Engineering,Beijing College of Social Administration,Beijing,China [5]Key Laboratory of Neuro-functional Information and Rehabilitation Engineering of the Ministry of Civil Affairs,Beijing,China

出　　处：《Neural Regeneration Research》2024年第7期1517-1522,共6页中国神经再生研究（英文版）

摘　　要：Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks,which have been widely applied in the field of central neurological diseases,such as stroke,Parkinson’s disease,and mental disorders.Although significant advances have been made in neuromodulation technologies,the identification of optimal neurostimulation paramete rs including the co rtical target,duration,and inhibition or excitation pattern is still limited due to the lack of guidance for neural circuits.Moreove r,the neural mechanism unde rlying neuromodulation for improved behavioral performance remains poorly understood.Recently,advancements in neuroimaging have provided insight into neuromodulation techniques.Functional near-infrared spectroscopy,as a novel non-invasive optical brain imaging method,can detect brain activity by measuring cerebral hemodynamics with the advantages of portability,high motion tole rance,and anti-electromagnetic interference.Coupling functional near-infra red spectroscopy with neuromodulation technologies offe rs an opportunity to monitor the cortical response,provide realtime feedbac k,and establish a closed-loop strategy integrating evaluation,feedbac k,and intervention for neurostimulation,which provides a theoretical basis for development of individualized precise neuro rehabilitation.We aimed to summarize the advantages of functional near-infra red spectroscopy and provide an ove rview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation,transcranial electrical stimulation,neurofeedback,and braincomputer interfaces.Furthermore,the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are summarized.In conclusion,functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central pellral reorganization to achieve better functional recovery form central nervous system diseases.

关 键 词：brain-computer interface cerebral neural networks functional near-infrared spectroscopy neural circuit NEUROFEEDBACK neurological diseases NEUROMODULATION non-invasive brain stimulation transcranial electrical stimulation transcranial electrical stimulation 

分 类 号：R741[医药卫生—神经病学与精神病学]