牙周探诊深度、附着丧失水平与阻塞性睡眠呼吸暂停严重程度的关联性  

An analysis of the association between the depth of periodontal exploration,the level of attachment loss,and the occurrence and severity of obstructive sleep apnea

作　　者：吴琬 曾海环 谢于鹏[2] 丁熙[1] WU Wan;ZENG Haihuan;XIE Yupeng;DING Xi(Department of Stomatology,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325015;Department of Sleep Center,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325015)

机构地区：[1]温州医科大学附属第一医院口腔科,浙江温州325015 [2]温州医科大学附属第一医院睡眠中心,浙江温州325015

出　　处：《温州医科大学学报》2023年第10期814-818,共5页Journal of Wenzhou Medical University

基　　金：温州市基础性科研项目(Y2020599)。

摘　　要：目的:探讨牙周探诊深度、附着丧失水平与阻塞性睡眠呼吸暂停(OSA)严重程度的关联性。方法:对2020年6月至2023年8月期间,在温州医科大学附属第一医院因打鼾怀疑为OSA并接受多导睡眠监测的157例受试者进行牙周探诊深度、附着丧失水平的检查。第一部分分为2组,健康人群(对照组,AHI<5次/h)61例和OSA组(AHI≥5次/h)96例;第二部分分为2组:轻度OSA组(5≤AHI<15次/h)30例和中重度OSA(AHI≥15次/h)66例。比较各组一般资料情况以及牙周指标水平差异,采用二元Logistic回归分析OSA发生的关联因素以及影响OSA病情严重度的关联因素。建立受试者工作特征(ROC)曲线,分析牙周探诊深度、附着丧失水平对OSA发生以及严重程度的评估价值。结果:OSA组与对照组间牙周探诊深度、附着丧失水平、舒张压差异有统计学意义(P<0.05)。二元Logistic回归分析显示,附着丧失水平增加(OR=1.225,95%CI=1.084~1.385,P=0.001)、牙周探诊深度增加(OR=1.545,95%CI=1.336~1.787,P<0.001)为影响OSA发生的关联因素。ROC曲线显示:附着丧失水平、探诊深度及两项联合评估OSA发生的ROC曲线下面积分别为0.752、0.905及0.927。轻度OSA组与中重度OSA组附着丧失水平差异有统计学意义(P<0.01)。二元Logistic回归分析显示,附着丧失水平(OR=1.256,95%CI=1.108~1.423,P<0.001)为中重度OSA的关联因素。ROC曲线显示,附着丧失水平评估OSA严重程度的ROC曲线下面积为0.770,对OSA严重程度有一定评估价值。结论:附着丧失水平、探诊深度与OSA的发生有关联性,附着丧失水平与OSA的严重程度有关联性。Objective:To investigate the correlation between the depth of periodontal exploration,the level of attachment loss,and the severity of obstructive sleep apnea(OSA).Methods:Totally 157 subjects suspected of OSA due to snoring and undergoing polysomnography monitoring between June 2020 and August 2023 were examined for periodontal probing depth and attachment loss level.According to the severity of the condition,they were divided as healthy group(control group)(AHI<5 times/h,61 cases),mild OSA group(5≤AHI<15 times/h,30 cases),moderate OSA group(15≤AHI<30 times/h,33 cases),and severe OSA group(AHI≥30 times/h,33 cases).The first part was divided into two groups:the control group(AHI<5 times/h)with 61 cases and the OSA group(AHI≥5 times/h)with 96 cases;The second part was divided into two groups:30 cases in the mild OSA group(5≤AHI<15 times/h)and 66 cases in the moderate to severe OSA group(AHI≥15 times/h).General information and differences in periodontal indicators were compared among each group,and binary Logistic regression was used to analyze the associated factors of OSA occurrence and the factors that affected the severity of OSA.The receiver operating characteristic(ROC)curve was established for evaluation and analysis of the depth of periodontal exploration,the level of attachment loss,and the occurrence and severity of OSA.Results:There were statistically significant difference in periodontal exploration depth,attachment loss level,and diastolic blood pressure between the OSA group and the control group(P<0.05).Binary Logistic regression showed that an increase in attachment loss level(OR=1.225,95%CI=1.084-1.385,P=0.001)and an increase in periodontal exploration depth(OR=1.545,95%CI=1.336-1.787,P<0.001)were associated factors affecting the occurrence of OSA.The ROC curve showed that the level of attachment loss,the depth of exploration,and the area under the ROC curve for joint assessment of OSA occurrence were 0.752,0.905,and 0.927,respectively.There was significant difference in the level of at

关 键 词：阻塞性睡眠呼吸暂停 慢性牙周炎 牙周探诊深度 附着丧失水平 

分 类 号：R737.11[医药卫生—肿瘤]