氯普鲁卡因在牙科焦虑患者牙拔除术中的应用效果  

Application Effect of Chloroprocaine in Tooth Extraction of Patients with Dental Anxiety

作　　者：雷飞 郑圆 雷小朋[1] LEI Fei;ZHENG Yuan;LEI Xiao-peng(Department of Stomatology,the Second Affiliated Hospital of Xi'an Medical University,Xi'an 710038,Shaanxi,China)

机构地区：[1]西安医学院第二附属医院口腔科,陕西西安710038

出　　处：《医学信息》2023年第22期101-104,共4页Journal of Medical Information

基　　金：西安医学院第二附属医院院级项目(编号:22KY0109)。

摘　　要：目的探讨氯普鲁卡因在牙科焦虑患者牙拔除术中的应用效果。方法选择2018年3月-2021年5月本院收治的伴有牙科焦虑的牙拔除术患者100例,随机分为研究组和对照组,每组50例。对照组使用2%盐酸利多卡因3.5 ml进行神经阻滞麻醉,研究组使用1.5%盐酸氯普鲁卡因注射液3.5 ml进行神经阻滞麻醉,麻醉起效后5 min进行手术。比较两组麻醉效果[麻醉起效时间、痛觉消失时间、痛觉恢复时间、拔牙时视觉模拟疼痛(VAS)评分],麻醉过程中的生理指标[麻醉前10 min、麻醉时、拔牙时、拔牙后10 min的收缩压(SBP)、舒张压(DBP)、心率]、心理指标(麻醉前10 min、麻醉时、拔牙时、拔牙后10 min的Kuttner、Frankl、Houpt评分)。结果研究组麻醉起效时间早于对照组,痛觉消失时间短于对照组,痛觉恢复时间早于对照组,拔牙时VAS评分低于对照组,差异有统计学意义(P<0.05);研究组拔牙时、拔牙后10 min的SBP、DBP、心率均低于对照组,差异有统计学意义(P<0.05);研究组拔牙时、拔牙后10 min的Kuttner评分低于对照组,Frankl、Houpt评分高于对照组,差异有统计学意义(P<0.05)。结论与利多卡因相比,氯普鲁卡因具有起效快、镇痛效果好的优势,将其应用于伴有牙科焦虑患者的牙拔除术中,有利于降低其血压和心率的波动,缓解其焦虑情绪。Objective To explore the effect of chloropprocaine in tooth extraction in patients with dental anxiety.Methods From March 2018 to May 2021,100 patients with dental anxiety who undergoing tooth extraction in our hospital were selected and randomly divided into study group and control group,with 50 patients in each group.The control group was treated with 2%lidocaine hydrochloride 3.5 ml for nerve block anesthesia,and the study group was treated with 1.5%chloroprocaine hydrochloride injection 3.5 ml for nerve block anesthesia.The operation was performed 5 min after the onset of anesthesia.The anesthesia effect[anesthesia onset time,pain disappearance time,pain recovery time,visual analogue scale(VAS)score during tooth extraction],physiological indexes during anesthesia[systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate at 10 min before anesthesia,during anesthesia,during tooth extraction,and 10 min after tooth extraction],and psychological indexes(Kuttner,Frankl,Houpt scores at 10 min before anesthesia,during anesthesia,during tooth extraction,and 10 min after tooth extraction)were compared between the two groups.Results The onset time of anesthesia in the study group was earlier than that in the control group,the pain disappearance time was shorter than that in the control group,the pain recovery time was earlier than that in the control group,and the VAS score at tooth extraction was lower than that in the control group,the differences were statistically significant(P<0.05).The SBP,DBP and heart rate of the study group were lower than those of the control group at the time of tooth extraction and 10 min after tooth extraction,and the differences were statistically significant(P<0.05).The Kuttner scores of the study group at the time of tooth extraction and 10 min after tooth extraction were lower than those of the control group,and the Frankl and Houpt scores were higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion Compared with lidocaine,chl

关 键 词：氯普鲁卡因 牙科焦虑 麻醉 牙拔除术 

分 类 号：R783.5[医药卫生—口腔医学]