危害分析和关键控制点在急诊药房药品效期管理的应用  

Application of Hazard Analysis and Critical Control Points Method in Management of Drug Expiry Dates in Emergency Pharmacy

作　　者：李素梅[1] Li Sumei(Third Affiliated Hospital,Inner Mongloia Medical College,Inner Mongloia Baotou 014010,China)

机构地区：[1]内蒙古医科大学第三附属医院,内蒙古包头014010

出　　处：《儿科药学杂志》2023年第11期25-28,共4页Journal of Pediatric Pharmacy

摘　　要：目的:探讨安全有效管理急诊药房药品效期的方法。方法:选取2021年1-6月急诊药房效期药品347种作为运用危害分析和关键控制点(HACCP)管理前的研究对象,2021年7-12月急诊药房效期药品353种作为运用HACCP管理后的研究对象,比较分析实施HACCP管理前后近效期药品在急诊药房的流通情况。具体步骤包括成立工作组、建立工作流程图、分析危害和评估风险、确定关键控制点(CCP)、建立关键限值(CL)、制定和实施HACCP计划、建立记录档案。结果:实施HACCP管理后,医院急诊药房近效期药品百分比降低,由3.09%下降到0.84%(P<0.05);药品报损率降低,由0.94‰下降到0.19‰(P<0.05)。结论:HACCP法用于急诊药房药品效期管理成果显著,值得推广应用。Objective:To explore safe and effective management in drug expiry dates in emergency pharmacy.Methods:A total of 347 types of drugs with expiry dates from Jan.to Jun.2021 were selected as the research subjects before implementation of Hazard Analysis and Critical Control Points(HACCP)management,and 353 types of drugs with expiry dates from Jul.to Dec.2021 were extracted as the research subjects after implementation of HACCP management.Comparative analysis was performed to assess the circulation of nearexpiry drugs in the emergency pharmacy before and after implementation of HACCP management.The specific steps included forming working group,establishing workflow diagram,analyzing hazards,assessing risks,identifying critical control points(CCP),setting critical limits(CL),developing and implementing HACCP regimen,and maintaining records.Results:After implementation of HACCP management,the proportion of near-expiry drugs in emergency pharmacy of the hospital decreased,from 3.09% to 0.84%(P<0.05).The drug wastage rate also decreased,from 0.94‰ to 0.19‰(P<0.05).Conclusion:The implementation of HACCP management in drug expiry dates in emergency pharmacy has yielded significant results and is worthy of wider promotion and application.

关 键 词：危害分析和关键控制点 药品 有效期 管理 急诊药房 

分 类 号：R969.3[医药卫生—药理学]