颌骨原发性非霍奇金淋巴瘤的临床及CT影像学特征分析  

Clinical and CT Imaging Analysis of Primary Non-Hodgkin Lymphoma of Jaw

作　　者：冯永静 文珊辉 王铁梅[1] 滕跃辉 夏舒 FENG Yongjing;WEN Shanhui;WANG Tiemei*;TENG Yuehui;XIA Shu(Department of Radiology,Nanjing Stomatological Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,China;Department of Pathology,Nanjing Stomatological Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,China)

机构地区：[1]南京大学医学院附属口腔医院,南京市口腔医院口腔颌面医学影像科,江苏南京210008 [2]南京大学医学院附属口腔医院,南京市口腔医院病理科,江苏省南京210008

出　　处：《口腔医学研究》2023年第11期978-981,共4页Journal of Oral Science Research

基　　金：江苏省自然科学基金(编号:BK20150089);江苏省南京市医学科技发展项目(编号:YKK15116)。

摘　　要：目的:探讨颌骨原发性非霍奇金淋巴瘤的临床及CT影像学特征。方法:回顾性分析经病理检查证实的颌骨原发性非霍奇金淋巴瘤24例患者临床及CT影像学特征。结果:24例颌骨原发性非霍奇金淋巴瘤中男17例,女7例。24例中16例患者在确诊前进行过抗炎治疗,6例患者在确诊前有拔牙治疗,2例患者行切开引流。骨质改变影像分型:溶骨型骨质破坏占17/24,混合型骨质破坏占5/24,牙槽骨吸收型占2/24。骨质破坏边缘的分型为:虫蚀型占8/24,浸润型占13/24,地图型占3/24,骨质破坏边缘分型在上下颌骨的不同部位具有明显统计学差异(P=0.003),下颌骨边缘破坏以虫蚀型为主,上颌骨病变边缘破坏以浸润型为主,发生在上下颌骨后部骨质改变溶骨型最多见。结论:颌骨原发性非霍奇金淋巴瘤具有一定的临床及影像学特征,这有助于对其疾病的临床及影像辨知。Objective:To analyze the clinical and CT imaging features of primary bone non-Hodgkin lymphoma(PB-NHL)of jaw retrospectively.Methods:The clinical and CT imaging features of 24 patients with PB-NHL of jaw confirmed by pathology were retrospectively analyzed.Results:Of the 24 patients with PB-NHL of the jaw,17 were male and 7 were female;16 underwent anti-inflammatory therapy before diagnosis,6 underwent tooth extraction,and 2 underwent incision and drainage.In the imaging classification of bone changes,osteolytic type accounted for 17/24,mixed type accounted for 5/24,and alveolar bone resorption accounted for 2/24.In the classification of the edge of bone destruction,moth-eaten destruction margin accounted for 8/24,infiltration destruction margin accounted for 13/24,and geographic type accounted for 3/24.There was significant statistical difference between different parts of mandible and mandible in the classification of bone destruction margin(P=0.003).Moth-eaten was the main type of mandibular edge damage,and infiltration was the main type of maxillary edge damage.Osteolytic type was the most common bone change in posterior mandible.Conclusion:PB-NHL of the jaw has certain clinical and imaging characteristics,which is helpful for the clinical and imaging recognition of the disease.

关 键 词：颌骨 原发性非霍奇金淋巴瘤 CT影像学特征 临床表现 

分 类 号：R739.8[医药卫生—肿瘤] R730.44[医药卫生—临床医学]