临床-超声模型预测子宫肌瘤经聚焦超声消融治疗后再次干预风险  

Clinical-ultrasound model for predicting reintervention risk of uterine fibroid after focused ultrasound ablation

作　　者：黄国华 唐辰典[2] 万丽丽 沈奕帆[2] 何佳[1,2] HUANG Guohua;TANG Chendian;WAN Lili;SHEN Yifan;HE Jia(Graduate School,Zunyi Medical University,Zunyi 563000,China;Department of Obstetrics and Gynecology,Suining Central Hospital,Suining 629000,China)

机构地区：[1]遵义医科大学研究生院,贵州遵义563000 [2]遂宁市中心医院妇产科,四川遂宁629000

出　　处：《中国介入影像与治疗学》2023年第11期658-663,共6页Chinese Journal of Interventional Imaging and Therapy

基　　金：超声医学工程国家重点实验室开放课题(2020KFA3009)。

摘　　要：目的观察临床-超声模型预测子宫肌瘤经聚焦超声消融(FUA)治疗后接受再次干预风险的价值。方法收集300例经FUA治疗的子宫肌瘤患者,将49例其后同一病灶接受再次干预者纳入观察组、其余251例归为对照组;比较组间临床、超声表现及随访所见,基于二元logistic回归建立预测再次干预风险的临床-超声模型,并观察其预测价值。结果组间年龄、生育史,MRI所见子宫体积、肌瘤位置、瘤骶距、肌瘤T2信号及强化程度差异均有统计学意义(P均<0.05),且二元logistic回归分析显示上述参数均为FUA治疗子宫肌瘤后接受再次干预风险的影响因素;据此建立的临床-超声模型预测再次干预风险的曲线下面积为0.882[95%CI(0.835,0.929)]。结论所获临床-超声模型可预测子宫肌瘤经FUA治疗后接受再次干预风险。Objective To observe the value of clinical-ultrasound model for predicting reintervention risk of uterine fibroid after focused ultrasound ablation(FUA).Methods Totally 300 patients with uterine fibroid who underwent FUA were enrolled.Patients with fibroid needing reintervention after FUA were divided into observation group(n=49),while the rest were enrolled in control group(n=251).Clinical,ultrasonic and follow-up data were compared between groups.Clinical-ultrasound model for predicting reintervention risk of uterine fibroid after FUA was established with binary logistic regression,and the predictive value of the model was observed.Results There were significant differences of age,reproductive history,uterine volume,fibroid location,fibroid-sacrum distance,fibroid T2 signal and enhancement degree showed on MRI between 2 groups(all P<0.05).Binary logistic regression analysis showed that the above indexes were all impact factors of reintervention risk of uterine fibroid after FUA.The area under the curve(AUC)of the clinical-ultrasound model for predicting reintervention risk of uterine fibroid after FUA was 0.882(95%CI[0.835,0.929]).Conclusion The established clinical-ultrasound model could be used to predict reintervention risk of uterine fibroid after FUA.

关 键 词：平滑肌瘤 子宫 超声疗法 

分 类 号：R737.33[医药卫生—肿瘤] R445.1[医药卫生—临床医学]