对比射频消融与腹腔镜子宫肌瘤剔除术治疗症状性子宫肌瘤效果:Meta分析  

Comparison on radiofrequency ablation and laparoscopic myomectomy for treating symptomatic uterine fibroids:Meta-analysis

作　　者：徐林 胡波[1] 赵东旭 史逸恺 姜小庆 倪才方[1] XU Lin;HU Bo;ZHAO Dongxu;SHI Yikai;JIANG Xiaoqing;NI Caifang(Department of Interventional Radiology,The First Affiliated Hospital of Soochow University,Suzhou 215000,China)

机构地区：[1]苏州大学附属第一医院介入放射科,江苏苏州215000

出　　处：《中国介入影像与治疗学》2023年第11期664-669,共6页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的采用meta分析比较射频消融(RFA)与腹腔镜子宫肌瘤剔除术(LM)治疗症状性子宫肌瘤的效果。方法检索并筛选PubMed、Web of Science、Embase、Cochrane Library、中国生物医学文献数据库(CBMdisc)、中国知网、维普数据库和万方医学网自建库至2022年8月31日关于RFA与LM治疗症状性子宫肌瘤的文献,并提取相关数据。采用Review Manager 5.3软件进行数据分析,观察RFA与LM治疗症状性子宫肌瘤效果的差异。结果共纳入11篇文献,包括994例症状性子宫肌瘤患者;其中RFA组497例、LM组497例。相比LM组,RFA组术中出血量、住院时间、手术时间及术后恢复正常活动所需时间均较少(OR=-19.87、-1.71、-1.85、-6.31,P均<0.05)而术后受孕率亦较低(OR=0.57,P<0.05);组间术后并发症发生率差异无统计学意义(P>0.05)。结论相比LM,RFA治疗症状性子宫肌瘤具有手术及住院时间短、术中出血量少、术后正常活动恢复快等优势,但对术后受孕率影响较大。Objective To compare the efficacy of radiofrequency ablation(RFA)and laparoscopic myomectomy(LM)for treating symptomatic uterine fibroids using meta-analysis.Methods Literature about RFA and LM for treating symptomatic uterine fibroids were searched in PubMed,Web of Science,Embase,Cochrane Library,China Biology Medicine disc(CBMdisc),CNKI,VIP databases and Wanfang Med Online from the establishment of database to August 31,2022,and the relevant data were extracted.Review Manager 5.3 was used for analysis,and the efficacy of treating symptomatic uterine fibroids were compared between RFA and LM.Results Totally 11 articles were enrolled,including 994 patients with symptomatic uterine fibroids,497 cases in RFA group and 497 cases in LM group.Compared with those in LM group,the intraoperative bleeding volume,hospital stay,operation time,postoperative recovery time to normal activities,as well as postoperative pregnancy rate were all lower in RFA group(OR=-19.87,-1.71,-1.85,-6.31,0.57,all P<0.05),while no significant difference of the incidence of postoperative complication was found between groups(P>0.05).Conclusion Compared with LM,RFA had advantages such as shorter operation time and hospital stay,lower intraoperative bleeding volume and faster recovery of normal postoperative activities for treating symptomatic uterine fibroids,but the impact of RFA on postoperative pregnancy rate was more obvious than LM.

关 键 词：平滑肌瘤 射频消融 腹腔镜 荟萃分析 

分 类 号：R737.33[医药卫生—肿瘤] R815[医药卫生—临床医学]