Enantioselective and Enantioconvergent Iron-Catalyzed C(sp^(3))-H Aminations to Chiral 2-Imidazolidinones  

作　　者：Tianjiao Cui Chen-Xi Ye Jordan Thelemann Daniel Jenisch Eric Meggers 

机构地区：[1]Fachbereich Chemie,Philipps-Universitat Marburg,Hans-Meerwein-Strasse 4,35043Marburg,Germany

出　　处：《Chinese Journal of Chemistry》2023年第17期2065-2070,共6页中国化学（英文版）

基　　金：the European Research Council(ERC)under the European Union's Horizon 2020 research and innovation programme(grant agreement No.883212).

摘　　要：Comprehensive Summary Enantioselective or enantioconvergent iron-catalyzed ring-closing C(sp^(3))-H aminations of N-aroyloxyurea through intermediate iron nitrene species provide chiral 2-imidazolidinones in up to 99%yield and with up to 95%ee(40 examples).This is a rare example in which sustainable iron catalysis is combined with C(sp^(3))-H amination and asymmetric catalysis.

关 键 词：Iron Asymmetric catalysis C-H activation AMINATION NITRENES HETEROCYCLES 

分 类 号：O621.25[理学—有机化学]