胎儿视网膜母细胞瘤超声表现  

Ultrasonic manifestations of fetal retinoblastoma

作　　者：高静[1] 栗河舟[1] 王铭[1] 李静[2] 周强 姜竹 张君玲[1] GAO Jing;LI Hezhou;WANG Ming;LI Jing;ZHOU Qiang;JIANG Zhu;ZHANG Junling(Department of Ultrasound,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Prenatal Diagnosis Center,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Pathology,Henan Children's Hospital,Zhengzhou 450018,China)

机构地区：[1]郑州大学第三附属医院超声科,河南郑州450052 [2]郑州大学第三附属医院产前诊断中心,河南郑州450052 [3]河南省儿童医院病理科,河南郑州450018

出　　处：《中国医学影像技术》2023年第11期1689-1692,共4页Chinese Journal of Medical Imaging Technology

基　　金：2020年度河南省医学适宜技术推广项目(SYJS2020080)。

摘　　要：目的观察胎儿视网膜母细胞瘤(RB)超声表现。方法回顾性分析7胎接受产前超声检查的单胎单侧RB胎儿资料,观察眼内病变二维、三维超声和血流成像表现。结果7胎眼内RB病灶均形态不规则、边缘不光整;6胎呈实性偏高回声,1胎呈无回声;6胎可见钙化,其中5胎点状钙化伴声影、1胎未伴声影;6胎呈分支状血流,与视网膜动脉连续,收缩期最高血流速度15.78~19.68 cm/s,阻力指数0.82~1.01,1胎呈稀疏点状;三维断层超声成像(TUI)显示4胎偏高回声肿块位于眼眶内,其余3胎未获得满意TUI。结论胎儿RB主要超声表现为眼内实性肿块伴钙化斑及高速高阻血流。Objective To observe the ultrasonicmanifestations of fetal retinoblastoma(RB).Methods Prenatal ultrasonographic data of 7 singleton fetuses with unilateral RB were retrospectively analyzed,and two-dimensional and three-dimensional ultrasound and blood flow imaging findings of intraocular lesions were observed.Results RB had irregular morphology and uneven edge in all 7 fetuses.Solid hyperechoic intraocular lesion was noticed in 6 fetuses,while intraocular lesion with poor transmission without echo was detected in 1 fetus.Calcifications were observed in 6 fetuses,including 5 of spotty calcification accompanied by sound shadow and 1 without sound shadow.The branched blood flow continuous with the retinal artery were found in 6 fetuses,with the maximum systolic blood flow velocity of 15.78—19.68 cm/s and resistance index of 0.82—1.01,with sparse punctate blood flow in 1 fetus.Three-dimensional tomographic ultrasound imaging(TUI)showed hyperechoic mass located in the eye socket in 4 fetuses,while TUI of the other 3 were not satisfactory.Conclusion Ultrasonic manifestations of fetal RB mainly included solid intraocular mass with calcified plaques as well as high speed and high resistance blood flow.

关 键 词：胎儿 视网膜母细胞瘤 超声检查 

分 类 号：R739.72[医药卫生—肿瘤] R445.1[医药卫生—临床医学]