薄荷精油现代研究进展  

Modern Research Progress on Peppermint Essential Oil

作　　者：刘慧[1] 殷佳[2] 傅春升[2] 李静蔚[2] 阴永辉[2] LIU Hui;YIN Jia;FU Chunsheng;LI Jingwei;YIN Yonghui(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]山东中医药大学附属医院,山东济南250014

出　　处：《山东中医药大学学报》2023年第6期812-818,共7页Journal of Shandong University of Traditional Chinese Medicine

基　　金：山东省重点研发计划(重大科技创新工程)项目(编号:2021CXGC010510)。

摘　　要：薄荷精油(PEO)是从薄荷的开花部位和叶子中提取出的一种常用精油,具有药食两用的特点,其分布范围及应用范围均较为广泛。通过检索相关文献,对PEO的化学成分、药理作用、临床应用及现有相关剂型等研究进行梳理。结果发现,PEO化学成分丰富,主要包括醇、酮、酯、萜烯、萜烷类化合物。药理作用主要包括抗菌、抗氧化及缓解胃肠、气管平滑肌痉挛等,另外还具有抗纤维化、保肝利胆、降血糖、抗病毒等作用。临床可用于治疗恶心呕吐、肠易激综合征、偏头痛等,近年来被制备成微囊、微乳等剂型,具有良好的发展前景。参考文献67篇。Peppermint essential oil(PEO)is a commonly used essential oil extracted from the flowering parts and leaves of Bohe(Menthae Haplocalycis Herba).It has the characteristics of medicine and food,and its distribution range and application range are relatively wide.In this paper,the chemical constituent,pharmacological action,clinical application and related dosage forms of PEO were sorted out by searching relevant literature.The results showed that PEO was rich in chemical constituents,including alcohols,ketones,esters,terpenes and terpene compounds.Pharmacological effects mainly include antibacterial activity,anti-oxidant,and relieving gastrointestinal and tracheal smooth muscle spasm,etc.In addition,it also has effects of anti-fibrosis,protecting liver,promoting bile secretion,lowering blood sugar and antivirus,etc.It can be used in clinical treatment of nausea and vomiting,irritable bowel syndrome,migraine and other diseases.In recent years,it has been prepared into microcapsules,microemulsions and other dosage forms,which have good development prospects.There are 67 references in total.

关 键 词：薄荷精油 化学成分 抗菌 抗氧化 肠易激综合征 偏头痛 剂型 药食两用 

分 类 号：R282.710.7[医药卫生—中药学]