基于临床特征及超声特征的等回声甲状腺乳头状癌的预测模型  

Development of a Nomogram Based on Clinical and Ultrasonographic Features to Predict Isoechoic Papillary Thyroid Carcinoma

作　　者：刘莹[1] 金朋 郭培杰[1] 陈松旺[1] Liu Ying;Jin Peng;Guo Peijie;Chen Songwang(Department of Ultrasound,Nanjing First Hospital,Nanjing Medical University,Nanjing 21oo00,China)

机构地区：[1]南京医科大学附属南京医院(南京市第一医院)超声科,南京市210000

出　　处：《中国超声医学杂志》2023年第10期1084-1087,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 建立基于临床、超声特征的等回声甲状腺乳头状癌的预测模型,并对模型的价值进行验证研究。方法 回顾性分析248例等回声甲状腺结节的临床特征和超声特征,按病理结果、BRAF基因、随访记录分为良性组与恶性组,对比两组的临床、超声特征,包括性别、年龄、≤45岁、直径、前后径/左右径、前后径/上下径、多发、位置、边界、边缘、声晕、微钙化、形状、血流。利用Logistic分析选择预测因素,建立模型并验证其价值。结果 男性、≤45岁、前后径/左右径>1、边界不清晰、边缘不光整、微钙化被确定为等回声甲状腺乳头状癌的预测因素,该模型的预测价值较高。结论 基于临床、超声特征的列线图可以简便、客观地识别等回声甲状腺乳头状癌。Objective The nomogram based on clinical and ultrasonographic features of isoechoic papillary thyroid carcinoma was established and its value was verified.Methods A retrospective analysis was performed on 248 patients with isoechoic thyroid nodule.The patients were divided into benign group and malignant group according to the pathological results,BRAF V6ooE and follow-up records.The clinical and ultrasonographic features of nodules were analyzed,including sex,age,<45,diameter,anteroposterior diameter/transverse diameter,anteroposterior diameter/longitudinal diameter,multifocal,location,boundary,margin,acoustic halo,microcalcification,shape,blood flow.This study used Logistic analysis to select predictive factors,built the predictive model and verified its value.Results The predictive factors of isoechoic papillary thyroid carcinoma were male,≤45,anteroposterior diameter/transverse diameter>l,ill-defined boundary,unsmooth margin,microcalcification.The predictive value of the nomogram was high.Conclusions The nomogram based on clinical and ultrasonographic features can simply and objectively identify isoechoic papillary thyroid carcinoma.

关 键 词：超声 等回声甲状腺乳头状癌 列线图 预测模型 

分 类 号：R736.1[医药卫生—肿瘤] R445.1[医药卫生—临床医学]