暴露类非随机研究偏倚风险评价工具(ROBINS-E 2022版)解读  

Risk of bias in nonrandomized studies of exposures(ROBINS-E 2022):an interpretation

作　　者：魏来武 陈削静 曹钰彬 苟攀 黄艳[3] 华成舸[1,2] 刘畅 WEI Laiwu;CHEN Xiaojing;CAO Yubin;GOU Pan;HUANG Yan;HUA Chengge;LIU Chang(State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of General Dentistry,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,P.R.China;Department of Oral and Maxillofacial Surgery&Department of Evidence-Based Dentistry,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,P.R.China;Department of Information Management&Department of Dental Informatics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心,四川大学华西口腔医院,口腔全科门诊,成都610041 [2]四川大学华西口腔医院,口腔颌面外科循证口腔医学教研室,成都610041 [3]四川大学华西口腔医院,信息管理部口腔医学信息学教研室,成都610041

出　　处：《中国循证医学杂志》2023年第11期1340-1350,共11页Chinese Journal of Evidence-based Medicine

基　　金：四川省科技计划项目(编号:2018SZ0181);四川大学华西口腔医院科研项目(编号:LCYJ2019-7)。

摘　　要：非随机研究是评估暴露(包括环境、职业和行为等暴露)对人类健康影响的重要方法。暴露类非随机研究偏倚风险评价工具(ROBINS-E)用于评价自然环境暴露或职业暴露观察性研究中的偏倚风险。本文主要介绍ROBINS-E 2022版的主要内容,包括制订背景、偏倚领域及相关的信号问题回答以及操作过程。Nonrandomized studies are an important method for evaluating the effects of exposures(including environmental,occupational,and behavioral exposures)on human health.Risk of bias in nonrandomized studies of exposures(ROBINS-E)is used to evaluate the risk of bias in natural or occupational exposure observational studies.This paper introduces the main contents of ROBINS-E 2022,including backgrounds,seven domains,signal questions and the operation process.

关 键 词：非随机研究 观察性研究 偏倚风险 暴露 系统评价 危险因素 

分 类 号：R-03[医药卫生]