2017—2020年江苏省40岁及以上常住居民脑卒中检出情况及危险因素分析  

Analysis of stroke detection and risk factors among permanent residents aged 40 and above in Jiangsu Province from 2017 to 2020

作　　者：耿侯跃 崔岚[2] 覃玉[2] 苏健[2] 陈路路 范习康 周金意[2] 陶然 GENG Hou-yue;CUI Lan;QIN Yu;SU Jian;CHEN Lu-lu;FAN Xi-kang;ZHOU Jin-yi;TAO Ran(Department of Epidemiology and Health Statistics,School of Public Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China;不详)

机构地区：[1]南京医科大学公共卫生学院流行病与卫生统计学系,江苏南京211166 [2]江苏省疾病预防控制中心慢性非传染病防制所,江苏南京210009

出　　处：《现代预防医学》2023年第21期3860-3865,共6页Modern Preventive Medicine

基　　金：江苏省“十四五”流行病学重点学科(ZDXK202250)。

摘　　要：目的 分析江苏省9市40岁及以上常住居民脑卒中及其主要危险因素的流行情况,为江苏省脑卒中防控提供数据支撑。方法 数据来源于2017—2020年在江苏省9个设区市11个项目点开展的脑卒中高危人群筛查和干预项目,采用多阶段随机抽样的方法,共124 131名40岁及以上常住居民纳入分析,采用χ^(2)检验比较不同特征人群脑卒中检出率,采用多因素logistic回归模型分析脑卒中影响因素并计算人群归因危险度。结果 124 131名调查对象中,3 641人患脑卒中,检出率为2.93%(标化检出率2.50%),其中男性高于女性(3.40%vs. 2.59%),城市高于农村(3.25%vs. 1.88%),随着年龄增长,检出率呈上升趋势(χ^(2)趋势=1 902.530,P<0.001)。多因素logistic回归分析显示,高血压(OR=2.84, 95%CI:2.60~3.10)、脑卒中家族史(OR=2.47, 95%CI:2.26~2.69)、心房颤动(OR=2.12, 95%CI:1.73~2.56)、血脂异常(OR=1.42, 95%CI:1.33~2.52)、糖尿病(OR=1.38, 95%CI:1.28~1.49)、缺乏体力活动(OR=1.29, 95%CI:1.20~1.39)和肥胖(OR=1.13, 95%CI:1.03~1.24)是脑卒中检出的危险因素。脑卒中检出最主要的归因因素为高血压(人群归因危险度为51.35%),其次为血脂异常(14.35%)。结论 江苏省40岁及以上居民脑卒中检出率与全国水平相近(2.58%),且主要归因于高血压、血脂异常等因素。Objective To analyze the prevalence of stroke and its main risk factors among residents aged 40 and above in 9 cities of Jiangsu Province,so as to provide data support for stroke prevention and control.Methods The data were collected from the screening and intervention projects for high-risk population of stroke carried out in 11 project sites of 9 districts and cities in Jiangsu Province from 2017 to 2020.A total of 124131 permanent residents aged 40 and above were included by multi-stage random sampling.The detection rates of stroke in people with different characteristics were compared by the Chi-square test.Multivariate Logistic regression model was used to analyze the influencing factors of stroke and calculate the population attributable risk.Results Of the 124131 subjects,3641 suffered from stroke,with a detection rate of 2.93%(standardized detection rate of 2.5%).The detection rate was higher in males than in females(3.40%vs.2.59%)and higher in urban areas than in rural areas(3.25%vs.1.88%),and the detection rate increased with age(χ^(2)trend=1902.530,P<0.001).Multivariate Logistic regression analysis showed that hypertension(OR=2.84,95%CI:2.60-3.10),family history of stroke(OR=2.47,95%CI:2.26-2.69),atrial fibrillation(OR=2.12,95%CI:1.73-2.56),dyslipidemia(OR=1.42,95%CI:1.33-2.52),diabetes mellitus(OR=1.38,95%CI:1.28-1.49),lack of physical activity(OR=1.29,95%CI:1.20-1.39),and obesity(OR=1.13,95%CI:1.03-1.24)were risk factors for stroke.The main attribution factor for stroke was hypertension,with population attributable risk of 51.35%,followed by dyslipidemia(14.35%).Conclusion The detection rate of stroke in residents aged 40 and over in Jiangsu Province is close to the national level(2.58%)and is mainly attributed to hypertension and dyslipidemia.

关 键 词：脑卒中 检出率 影响因素 人群归因危险度 

分 类 号：R743.3[医药卫生—神经病学与精神病学]