化妆品中大麻二酚的检测方法及溯源研究进展  

Advances of detection methods and traceability study of cannabidiol in cosmetics

作　　者：牛可歆 赵霞 廉洁[1] NIU Kexin;ZHAO Xia;LIAN Jie(School of Investigation,People’s Public Security University of China,Beijing 100038,China;Beijing Branch of National Drug Laboratory,Beijing 100164,China)

机构地区：[1]中国人民公安大学侦查学院,北京100038 [2]国家毒品实验室北京分中心,北京100164

出　　处：《分析试验室》2023年第10期1386-1394,共9页Chinese Journal of Analysis Laboratory

基　　金：中央高校基本科研业务费(2022JKF02006);国家重点研发计划子课题(2017YFC0803604)资助。

摘　　要：大麻二酚(CBD)是大麻的主要成分,因其具有强大的抗炎抗氧、美白保湿等功效,被越来越多地应用到化妆品中,但受CBD来源和安全性问题的影响,我国对其在化妆品领域的应用进行严格管控。CBD主要通过提取大麻植株中的大麻素获得,其复杂的成分和多样的化妆品品类,使得对化妆品中CBD的前处理和分析检测面临巨大的挑战。近年来,已开发出多种化妆品中大麻素的分析方法,液液萃取是最常用的前处理方法,色谱-质谱联用技术是首选的检测方法,同时便携式仪器设备的多种快检方法也有望应用于化妆品中大麻素的检测。本文综述了化妆品中CBD前处理和检验方法的研究进展,并结合CBD的主要来源,探讨了基于上述检验方法的化妆品原料溯源问题,以期为开展相关科学研究提供参考和借鉴。Cannabidiol(CBD) is the main component of cannabis.Because of its powerful anti-inflammatory,antioxidant,whitening and moisturizing effects,it is increasingly used in cosmetics.However,due to the source of CBD and safety issues,China imposes strict controls on its cosmetics sector.CBD in cosmetics mainly comes from extraction of cannabinoids plants.The complexity of its components and the diversity of cosmetic categories make the pretreatment analysis and detection of CBD in cosmetics face huge challenges.In recent years,a variety of analytical methods for detection of cannabinoids in cosmetics have been developed.Liquid-liquid extraction is the most used pretreatment method,and chromatography-mass spectrometry is the preferred laboratory analysis method.With portable instruments and equipment used,a variety of rapid detection methods are also expected to be applied to the detection of cannabinoids in cosmetics.This paper compares the existing detection technologies for detection of cannabinoids in cosmetics,and refers to the idea of chemical typing of cannabis plants,discusses the application of existing detection technologies in the traceability of components,and prospects for the development direction of cannabinoid detection,providing reference for related scientific research.

关 键 词：大麻二酚 化妆品 色谱-质谱联用技术 大麻素 溯源 

分 类 号：O65[理学—分析化学]