乙型肝炎患者免疫球蛋白检验的方法与结果分析  

Method and Result Analysis of Immunoglobulin Testing in Hepatitis B Patients

作　　者：张梅 ZHANG Mei(Ezhou Traditional Chinese Medicine Hospital,Ezhou 436000,China)

机构地区：[1]鄂州市中医医院,湖北鄂州436000

出　　处：《中国医药指南》2023年第33期126-128,共3页Guide of China Medicine

摘　　要：目的讨论检验乙型肝炎患者免疫球蛋白的方法,分析检验结果。方法选取2021年10月至2022年10月本院已确诊的乙型肝炎患者60例组成试验组,同时期内选择60例健康体检者组成对比组,两组均采取免疫球蛋白检验。分析比较两组免疫球蛋白指标,试验组合并肝硬化与未合并肝硬化免疫球蛋白指标、失代偿期与代偿期免疫球蛋白指标及试验组治疗前后免疫球蛋白指标变化。结果试验组免疫球蛋白M、免疫球蛋白G、免疫球蛋白A指标均高于对比组,P<0.05,差异有统计学意义。分析试验组免疫球蛋白检验结果发现,合并肝硬化患者的免疫球蛋白M、免疫球蛋白G、免疫球蛋白A指标高于未合并肝硬化患者,P<0.05,差异有统计学意义。对肝硬化患者的检验结果进行分析发现,处于失代偿期患者的免疫球蛋白M、免疫球蛋白G、免疫球蛋白A指标比代偿期患者指标高,P<0.05,差异有统计学意义。对试验组患者实施为期半年的治疗后发现,治疗3个月、治疗6个月的免疫球蛋白M、免疫球蛋白G、免疫球蛋白A指标低于治疗前,且治疗6个月的各项指标水平低于治疗3个月时的水平,P<0.05,差异有统计学研究意义。结论检验免疫球蛋白可帮助医师诊断乙型肝炎患者病情,明确患者病情发展阶段,对于辅助医师制订针对性治疗方案有重要意义。Objective To discuss the methods for testing immunoglobulin in patients with hepatitis B and analyze the test results.Methods 60 confirmed hepatitis B patients in our hospital from October 2021 to October 2022 were selected as the experimental group,while 60 healthy individuals were selected as the control group during the same period.Both groups underwent immunoglobulin testing.Analyze and compare two sets of immunoglobulin indicators,including the immunoglobulin indicators in the experimental group with and without cirrhosis,the immunoglobulin indicators in the decompensated and compensated phases,and the changes in immunoglobulin indicators in the experimental group before and after treatment.Results The indicators of immunoglobulin M,immunoglobulin G,and immunoglobulin A in the experimental group were higher than those in the control group,with a statistically significant difference(P<0.05).Analysis of the immunoglobulin test results in the experimental group showed that the immunoglobulin M,immunoglobulin G,and immunoglobulin A indicators in patients with concomitant liver cirrhosis were higher than those in patients without concomitant liver cirrhosis,with a statistically significant difference(P<0.05).Analysis of the test results of patients with liver cirrhosis found that the indicators of immunoglobulin M,immunoglobulin G,and immunoglobulin A in patients in the decompensated phase were higher than those in patients in the compensatory phase,with a statistically significant difference(P<0.05).After six months of treatment for the experimental group of patients,it was found that the levels of immunoglobulin M,immunoglobulin G,and immunoglobulin A were lower after 3 and 6 months of treatment than before treatment,and the levels of various indicators after 6 months of treatment were lower than those at 3 months of treatment,P<0.05,with statistically significant differences.Conclusions Testing immunoglobulin can help physicians diagnose the condition of hepatitis B patients,clarify the stage of disease develo

关 键 词：免疫球蛋白 肝硬化 乙型肝炎 代偿期 

分 类 号：R575.2[医药卫生—消化系统]