服用集采二甲双胍2型糖尿病患者远程药学随访分析  

Remote pharmacy follow-up analysis of patients with type 2 diabetes taking collectively-purchased metformin

作　　者：谢灵波 陈勤朴 何莹[1] 徐钊 杨周萍 邓丽君[1] 魏照星 XIE Ling-bo;CHEN Qin-pu;HE Ying(Dept.of Pharmacy,The Seventh Affiliated Hospital of Sun Yat-Sen University,Shenzhen 518107,China;不详)

机构地区：[1]中山大学附属第七医院药学部,广东深圳518107 [2]中国科学院大学深圳医院药学部,广东深圳518106

出　　处：《中国处方药》2023年第11期73-76,共4页Journal of China Prescription Drug

基　　金：深圳市光明区软科学研究项目基金(2021R01126)。

摘　　要：目的 了解服用集采二甲双胍2型糖尿病患者情况,为医生开具集采二甲双胍、患者服用集采二甲双胍提供相关数据,为药师进行集采药品宣教与药学随访服务提供相关数据参考。方法 自拟随访问卷,对2021年7月~2023年3月期间某院服用集采二甲双胍的2型糖尿病门诊患者进行远程药学随访,分析患者总体情况,并比较换药组(由原研二甲双胍换为集采中选二甲双胍的患者)与集采组(仅服用集采中选二甲双胍的患者)在集采与一致性评价政策认知度、服用集采二甲双胍的疑虑、不良反应发生情况、血糖控制情况等方面的差异。结果44.00%的患者完全不了解国家集采与一致性评价政策,仅15.20%的患者很清楚国家集采与一致性评价政策,换药组相比集采组更了解国家集采及一致性政策(P <0.05);75.20%的患者对正在服用的集采二甲双胍充满信心,不存在对其疗效及不良反应的疑虑,仅24.80%的患者对集采二甲双胍存在疑虑,换药组对集采二甲双胍疑虑比例高于集采组(P <0.05);44.00%的患者血糖控制达标,32.00%的患者血糖控制不达标,24.00%的患者未进行血糖监测,换药组与集采组血糖控制达标率差异无统计学意义(P> 0.05);37.60%的患者出现不良反应,不良反应以胃肠道反应为主,换药组与集采组在不良反应发生率方面差异无统计学意义(P> 0.05)。结论 集采二甲双胍不良反应与原研药相当,患者血糖控制情况尚可,但部分患者对集采二甲双胍疗效与不良反应有疑虑,医生药师应对患者做好集采相关的宣教及后续的药学随访服务。Objective To investigate the situations of patients with type 2 diabetes taking collectively-purchased metformin,which providing data for doctors to prescribe collectively-purchased metformin and patients to take metformin,and providing relevant data reference for pharmacists to carry out collectively-purchased drugs education and pharmacy follow-up services.Methods Making remote pharmacy follow-up questionnaire for out-patients with type 2 diabetes who took collectively-purchased metformin from July 2021 to March 2023 in a hospital,analyzed overall patient situation.The differences of awareness of collectively-purchased drugs and the consistency evaluation policy,doubts about taking collectivelypurchased metformin,occurrence of adverse drug reactions and blood glucose control between the drug change group(those patients who switched from original research metformin to collectively-purchased metformin) and the collectively-purchased group(only taking collectively-purchased metformin) were compared.Results 44.00% patients did not understand the national collectively-purchased drugs and consistency evaluation policy at all,while only 15.20% patients knew the national collectively-purchased drugs and consistency evaluation policy very well.Patients in the drug change group knew the national collectively-purchased drugs and consistency evaluation policy much better than the collectively-purchased group.75.20% patients were confident in the collectively-purchased metformin which they were taking,who had no doubts about the efficacy and adverse drug reactions.Only 24.80% patients had doubts about collectively-purchased metformin.The proportion of doubts about collectively-purchased metformin in the drug change group was higher than that in the collectively-purchased group.44.00% patients whose blood glucose level reached the standard,while 32.00% patients did not meet the blood glucose control standard.24.00% of the patients did not carry out blood glucose monitoring.There was no significant difference in the glucose-t

关 键 词：2型糖尿病 远程药学随访 不良反应 集中采购 仿制药 二甲双胍 

分 类 号：R969[医药卫生—药理学]