无心脑血管疾病危险因素成年受检者颈动脉管腔结构与血流速度分布特征及相关性分析  

Distribution characteristics and correlation analysis of carotid artery lumen structure and blood flow velocity in adult subjects without risk factors for cardiovascular and cerebrovascular disease

作　　者：李佳珊 华扬[1] 马兆毅 贾凌云[1] 脑卒中高危人群筛查脑颈动脉规范化评估数据库课题组 Li Jiashan;Hua Yang;Ma Zhaoyi;Jia Lingyun;Carotid Artery Ultrasound Project Group(CAUPG)(Department of Vascular Ultrasound,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;不详)

机构地区：[1]首都医科大学宣武医院血管超声科,北京100053 [2]国家卫生健康委能力建设和继续教育中心 [3]不详

出　　处：《中国脑血管病杂志》2023年第11期740-747,共8页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的分析无心脑血管病史及危险因素的成年受检者不同年龄、性别、侧别的颈动脉管腔结构、血流速度差异性,以及血流速度与颈动脉指数(CI)的相关性。方法纳入2019年12月至2021年12月国内53家医院筛查既往无心脑血管病史及其危险因素的健康成年受检者2738例(男787例,女1951例),记录颈动脉超声检查结果,分析年龄[40岁以上年龄组(≥40岁组)与40岁以下年龄组(<40岁组)]、性别、左右侧别之间颈总动脉(CCA)、颈动脉球部(BULB)、颈内动脉(ICA)的内径(D_(CCA)、D_(BULB)、D_(ICA))及血流速度[收缩期峰值流速(PSV),包括双侧CCA和ICA的PSV(PSV_(CCA)、PSV_(ICA));舒张期末流速(EDV),包括双侧CCA和ICA的EDV(EDV_(CCA)、EDV_(ICA))]的差异性。分析组间CI[CI_(BULB/ICA)(D_(BULB)与D_(ICA)比值)、CI_(BULB/CCA)(D_(BULB)与D_(CCA)比值)、CI_(ICA/CCA)(D_(ICA)与D_(CCA)比值)]的差异性并与对应颈动脉血流速度进行相关性分析。结果(1)≥40岁组D_(CCA)、D_(BULB)、D_(ICA)均大于<40岁组[分别为6.2(5.7,6.7)mm比6.0(5.6,6.4)mm,7.0(6.4,7.8)mm比6.7(6.1,7.4)mm,4.6(4.1,5.1)mm比4.5(4.1,5.0)mm]。男性D_(CCA)、D_(BULB)、D_(ICA)均大于女性[分别为6.2(5.8,6.7)mm比6.0(5.6,6.4)mm,7.1(6.4,7.8)mm比6.7(6.1,7.4)mm,4.8(4.4,5.3)mm比4.4(4.1,4.9)mm],差异均有统计学意义(均P<0.01)。左侧D_(CCA)小于右侧[6.0(5.6,6.5)mm比6.1(5.7,6.5)mm],右侧D_(ICA)小于左侧[4.5(4.0,5.0)mm比4.5(4.1,5.0)mm],差异均有统计学意义(均P<0.05)。(2)<40岁组受检者的PSV_(CCA)、PSV_(ICA)、EDV_(CCA)、EDV_(ICA)均高于≥40岁组[分别为95(80,112)cm/s比77(63,92)cm/s,85(72,98)cm/s比77(65,92)cm/s,28(24,33)cm/s比26(21,31)cm/s,33(28,39)cm/s比32(26,38)cm/s],女性PSV_(ICA)、EDV_(CCA)、EDV_(ICA)均高于男性[分别为84(71,97)cm/s比79(66,95)cm/s,28(23,33)cm/s比27(22,32)cm/s,34(28,40)cm/s比30(25,35)cm/s],左侧PSV_(CCA)、EDV_(CCA)均高于右侧[分别为91(75,108)cm/s比87(72,104)cm/s,28(23,33)cm/s比27(22,32)cm/s],差异均有统计学意义(�Objective The differences of carotid artery structure and blood flow velocity among adult subjects without risk factors of cardiovascular and cerebrovascular disease regarding different age,gender,side,blood flow velocity difference and the correlation of blood flow velocity with common carotid artery index(CI)were analyzed.Methods All of the 2738 adults(787 males,1951 females)without risk factors for cardiovascular and cerebrovascular diseases were continuously included in the multicenter carotid ultrasound database of 53 hospitals in China from December 2019 to December 2021.Carotid ultrasound results were recorded.The differences of the diameter of common carotid artery(CCA,D_(CCA)),carotid bulb(BULB,D_(BULB)),internal carotid artery(ICA,D_(ICA))and blood flow velocity(peak systolic flow velocity[PSV],including bilateral CCA and ICA PSV[PSV_(CCA),PSV_(ICA)];end-diastolic flow velocity(EDV),including bilateral CCA and ICA EDV[EDV_(CCA),EDV_(ICA)])between age(over 40 years old and under 40 years old),gender,left and right side were analyzed.The differences of CI(CI_(BULB/ICA)[ratio of D_(BULB) to D_(ICA)],CI_(BULB/CCA)[ratio of D_(BULB) to D_(CCA)],CI_(ICA/CCA)[ratio of D_(ICA) to D_(CCA)])between groups were analyzed,and the correlation with corresponding carotid artery blood flow velocity was analyzed.Results(1)The D_(CCA),D_(BULB) and D_(ICA) in age group over 40 years old were greater than those in age group under 40 years old(6.2[5.7,6.7]mm vs.6.0[5.6,6.4]mm,7.0[6.4,7.8]mm vs.6.7[6.1,7.4]mm,4.6[4.1,5.1]mm vs.4.5[4.1,5.0]mm).D_(CCA),D_(BULB) and D_(ICA) in male were higher than those in female(6.2[5.8,6.7]mm vs.6.0[5.6,6.4]mm,7.1[6.4,7.8]mm vs.6.7[6.1,7.4]mm,4.8[4.4,5.3]mm vs.4.4[4.1,4.9]mm).The differences were statistically significant(P<0.01 for all).D_(CCA) on the left side was smaller than that on the right side(6.0[5.6,6.5]mm vs.6.1[5.7,6.5]mm),and D_(ICA) on the right side was smaller than that on the left side(4.5[4.0,5.0]mm vs.4.5[4.1,5.0]mm),with statistical significance(both P<0.05).(2)The PSV_(CC

关 键 词：颈动脉流速 颈动脉管腔结构 颈动脉指数 超声 

分 类 号：R743[医药卫生—神经病学与精神病学]