Modifying the progression of Parkinson's disease through movement interventions:multimodal quantification of underlying mechanisms  

作　　者：Manuel Bange Damian Marc Herz Dumitru Ciolac Gabriel Gonzalez-Escamilla Sergiu Groppa 

机构地区：[1]Section of Movement Disorders and Neurostimulation,Department of Neurology,Focus Program Translational Neuroscience(FTN),University Medical Center of the Johannes Gutenberg-University Mainz,Mainz,Germany

出　　处：《Neural Regeneration Research》2024年第8期1651-1652,共2页中国神经再生研究（英文版）

摘　　要：Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement disorder.The pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structu re and function of distributed brain networks.Togethe r,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).

关 键 词：alterations MOVEMENT 

分 类 号：R742.5[医药卫生—神经病学与精神病学]