Millimetric devices for nerve stimulation:a promising path towards miniaturization  

作　　者：Ryan M.Dorrian Anna V.Leonard Antonio Lauto 

机构地区：[1]Spinal Cord Injury Research Group,School of Biomedicine,The University of Adelaide,Adelaide,SA,Australia [2]School of Science,Western Sydney University,Penrith,NSW,Australia

出　　处：《Neural Regeneration Research》2024年第8期1702-1706,共5页中国神经再生研究（英文版）

基　　金：funded by Western Sydney University and The University of Adelaide;supported by the Morton Cure Paralysis Fund and the Neurosurgical Research Foundation。

摘　　要：Nerve stimulation is a rapidly developing field,demonstrating positive outcomes across several conditions.Despite potential benefits,current nerve stimulation devices are large,complicated,and are powered via implanted pulse generators.These facto rs necessitate invasive surgical implantation and limit potential applications.Reducing nerve stimulation devices to millimetric sizes would make these interventions less invasive and facilitate broader therapeutic applications.However,device miniaturization presents a serious engineering challenge.This review presents significant advancements from several groups that have overcome this challenge and developed millimetricsized nerve stimulation devices.These are based on antennas,mini-coils,magneto-electric and optoelectronic materials,or receive ultrasound power.We highlight key design elements,findings from pilot studies,and present several considerations for future applications of these devices.

关 键 词：biomedical engineering deep brain stimulation electrical engineering electrical stimulation NEUROMODULATION peripheral nerve stimulation 

分 类 号：R741[医药卫生—神经病学与精神病学]