DNA介导荧光铜纳米簇的合成及表征——推荐一个研究型综合化学实验  

Synthesis and Characterization of DNA-Mediated Fluorescent Copper Nanoclusters:Recommending A Research-Oriented Comprehensive Chemical Experiment

作　　者：李俊彬 李承麟 骆嘉琪 陈惠 卿志和[1] Junbin Li;Chenglin Li;Jiaqi Luo;Hui Chen;Zhihe Qing(College of Chemistry and Chemical Engineering,Changsha University of Science&Technology,Changsha 410114,China)

机构地区：[1]长沙理工大学化学化工学院,长沙410114

出　　处：《大学化学》2023年第9期122-130,共9页University Chemistry

基　　金：国家自然科学基金(22222402,22204008);湖南省普通高等学校教学改革研究项目(HNJG-2021-0459);长沙理工大学教学改革研究项目(XJG21-106)。

摘　　要：为达到科研反哺教学、教学创新促进人才培养的目标,有必要对传统化学实验进行改革。在此,基于课题组人员前期科研成果,设计了一个研究型综合化学实验,以DNA分子为模板合成与表征荧光铜纳米簇,并获取稳定合成荧光铜纳米簇的条件。实验内容包括纳米簇的合成、基本光谱分析仪器的使用、光谱数据的处理等。实验交叉融合分析化学、生物化学、纳米科学等多学科前沿知识,实验条件简单温和,实验时长合理,满足实验教学的各项要求,能充分激发学生的科研兴趣、提升综合能力,具有很好的实验教学推广价值。To achieve the goals of scientific research on back-feeding teaching and teaching innovation to promote personnel training,reforming traditional chemical experiments is necessary.Based on previous scientific research achievements of the research team,a comprehensive chemical experiment was designed to synthesize and characterize fluorescent copper nanoclusters using DNA molecules as templates,and the conditions for stable synthesis of fluorescent copper nanoclusters were obtained.The experiment included the synthesis of nanoclusters,use of basic spectral analysis instruments,and spectral data processing.The experiment integrates the frontier knowledge of analytical chemistry,biochemistry,and nanoscience,among others.The experimental conditions were simple and mild,and the experimental duration was reasonable,meeting the requirements of experimental teaching,stimulating students’interest in scientific research,enhancing their comprehensive ability,and promoting experimental teaching.

关 键 词：DNA 铜纳米簇 荧光 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]