放疗在胃癌围手术期中的应用及局限  

Application and Limitation of Radiotherapy in Perioperative Period of Gastric Cancer

作　　者：徐文婧 孙恒文[1] XU Wen-jing;SUN Heng-wen(Department of Radiotherapy,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080,China;The Second School of Clinical Medicine,Southern Medical University,Guangzhou 510080,China)

机构地区：[1]南方医科大学附属广东省人民医院(广东省医学科学院)放疗科,广州510080 [2]南方医科大学第二临床医学院,广州510080

出　　处：《循证医学》2023年第4期244-251,256,共9页The Journal of Evidence-Based Medicine

基　　金：广州市科技计划项目(201804010132)。

摘　　要：胃癌是常见的消化道恶性肿瘤之一,手术切除是其主要的治疗措施,但是术后复发率高,放疗作为提高胃癌局部控制率的重要手段而备受关注,虽然有一些研究证明了放疗在胃癌中的价值,但仍存在大量问题亟待解决。本文从放疗在胃癌治疗中的时机选择、靶区控制、放疗新技术的应用以及免疫治疗联合放疗等方面进行综述,旨在为优化胃癌治疗模式,为实现胃癌精准治疗、个体化治疗提供线索。Gastric cancer was one of the common malignancies of the digestive tract,surgical resection was the main treatment,but the postoperative recurrence rate was high.Radiotherapy as an important means to improve the local control rate of gastric cancer had attracted much attention.Although plenty of studies had proved the value of radiotherapy in gastric cancer,there were still a lot of problems to be solved.This article reviewed the timing of radiotherapy in the treatment of gastric cancer,target volume control,the application of new radiotherapy technologies,and immunotherapy combined with radiotherapy,aiming to optimize the treatment mode of gastric cancer and provide clues for the realization of precise and individualized treatment of gastric cancer.

关 键 词：胃癌 放疗 靶区移动度 免疫联合治疗 质子治疗 

分 类 号：R735.2[医药卫生—肿瘤] R730.55[医药卫生—临床医学]