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作 者:叶慧珍 张颖[1] YE Hui-zhen;ZHANG Ying(Staff and Faculty Clinic,State Key Laboratory of Oncology in South China//Collaborative Innovation Center for Cancer Medicine,Sun Yat-Sen University Cancer Center,Guangzhou 510060,China)
机构地区:[1]中山大学肿瘤防治中心职工保健科//华南肿瘤学国家重点实验室//肿瘤医学协同创新中心,广东广州510060
出 处:《中山大学学报(医学科学版)》2023年第6期1068-1074,共7页Journal of Sun Yat-Sen University:Medical Sciences
基 金:广东市科学技术局基础与应用基础研究专题基金(SL2022A04J01651)。
摘 要:【目的】本研究旨在探讨医院职工肺癌患病情况,提高职工肿瘤防治水平。【方法】收集全球疾病负担数据库中国肺癌疾病数据和某三甲肿瘤专科医院职工2009-2021年年度体检数据、随访病理资料和生存随访数据进行比较分析。【结果】近年来,该院职工和中国人群肺癌的年龄标准化患病率均不断上升。该院职工肺癌年龄标准化患病率高于中国人群,但年龄标准化死亡率较低。职工肺癌患病率年度增长率也高于中国人群(平均年度变化百分比AAPC 13.0%vs.4.1%)。增加胸部CT平扫为常规体检项目后(2014-2021年),职工新确诊的肺癌病例的早期病例占比相较于未增加胸部CT检查前(2009-2013年)明显增加,提示胸部CT平扫体检可能有利于肺癌早期筛查。【结论】该院职工肺癌患病率及其增长速度均高于中国人群,但死亡率较低。胸部CT平扫体检可能对于肺癌的早筛查早治疗具有重要的意义。【Objective】To investigate the prevalence of lung cancer among medical staff in a hospital and promote the level of cancer prevention and treatment.【Methods】The annual physical examination data,follow-up pathology and surviv‐al data from 2009 to 2021 in a tertiary cancer hospital were collected and then compared with data of lung cancer in China from the global burden of disease database(GBD database).【Results】The age-standardized prevalence of lung cancer have been continuously increasing in both populations in recent years.The age-standardized prevalence of lung cancer among medical staff was higher than that in Chinese population,but the age-standardized mortality was lower.The Aver‐age Annual Percent Change(AAPC)of lung cancer prevalence among staff was higher than that in Chinese population(13.0%vs.4.1%),indicating a higher growth rate.The proportion of newly diagnosed early-stage lung cancer in 2014-2021 was significantly higher than that before adding plain chest CT scan in routine physical examination(2009-2013),suggesting the benefit of chest CT scan for early screening of lung cancer.【Conclusion】The prevalence and growth rate of lung cancer among the staff were higher than those in Chinese population,but the mortality was lower.Plain chest CT scan is essential for early screening and treatment of lung cancer.
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