超脉冲CO_(2)激光治疗眼睑肿物的疗效与安全性评估  

Efficacy and safety assessment of ultrapulse carbon dioxide laser in treating eyelid tumors

作　　者：王丁巧 李作红[1] 高无忧 曲艺欣 毛真[1] 林羡钗[1] WANG Dingqiao;LI Zuohong;GAO Wuyou;QU Yixin;MAO Zhen;LIN Xianchai(State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou 510060,China)

机构地区：[1]中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州510060

出　　处：《眼科学报》2023年第8期541-550,共10页Eye Science

摘　　要：目的:评估超脉冲二氧化碳(CO_(2))激光治疗不同类型眼睑肿物的疗效和安全性。方法:纳入50例眼睑肿物患者,其中男12例、女38例。患者年龄4~84岁。肿物类型包括眼睑色素痣、睑黄瘤、分裂痣、眼睑疣等,其中25例累及眼睑灰线,10例肿物直径>10 mm。所有患者接受超脉冲CO_(2)激光治疗,并进行术后随访。治疗效果通过术后数码照片评估,同时记录术后1个月并发症发生情况。结果:50例眼睑肿物总体治愈率为92%,有效率达到100%。4例眼睑色素痣在治疗后1个月内复发。术后并发症主要包括轻微倒睫(5例)、睫毛稀疏部分缺失(4例)和瘢痕增生及色素沉着(4例),未出现其他严重并发症。结论:对于眼睑肿物,特别是睑缘肿物及大肿物,超脉冲CO_(2)激光是一种更为精确、微创、安全、有效的治疗方法,可作为眼睑肿物治疗的优选方案。Objective:To evaluate the efficacy and safety of ultrapulse carbon dioxide(CO_(2))laser in the treatment for various types of eyelid tumors.Methods:A total of 50 patients,including 12 males and 38 females,with eyelid tumors were included in the study.The age range is from 4 to 84 years.The tumors found in our study include eyelid pigmented nevus,xanthelasma,divided nevus,and molluscum.Among them,25 cases involved the gray line of the eyelid,and 10 cases had a tumor diameter greater than 10 mm.All patients underwent ultrapulse CO_(2)laser treatment and postoperative follow-up.The treatment outcomes were assessed through digital photos,and complications were recorded one month after surgery.Results:The total cure rate of the 50 cases of eyelid tumors in our study was 92%,with the effective rate reaching 100%.4 cases of eyelid pigmented nevi recurred within one month after treatment,while all other patients were cured.Postoperative complications mainly included minor trichiasis(5 cases),partial sparse to absent eyelashes(4 cases),and hypertrophic scar with hyperpigmentation(4 cases).No other serious complications were reported in our study.Conclusions:For eyelid tumors,especially eyelid margin and larger tumors,the ultrapulse CO_(2)laser is a more precise,minimally invasive,safe and effective treatment method.It can be used as a preferred treatment option for eyelid tumors,and should be promoted widely in clinical practice.

关 键 词：超脉冲CO_(2)激光 眼睑肿物 眼睑缘 治疗效果 并发症 

分 类 号：R739.7[医药卫生—肿瘤]