纳米炭混悬注射液联合聚氨基葡萄糖羧酸钠医用生物胶体液在甲状腺癌根治术中的应用效果  

Effect of Carbon Nanoparticles Suspension Injection and Polyglucosamine Sodium Carboxylate Medical Biocolloid Liquid in Radical Thyroidectomy for Thyroid Cancer

作　　者：张鹏[1] 胡昆鹏[1] ZHANG Peng;HU Kunpeng(The Thyroid and Breast Surgery Department of Lingnan Hospital,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,Guangdong,China)

机构地区：[1]中山大学附属第三医院岭南医院甲状腺乳腺外科,广东广州510630

出　　处：《中国药物滥用防治杂志》2023年第11期1980-1983,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:探讨术中联合纳米炭混悬注射液和聚氨基葡萄糖羧酸钠医用生物胶体液对甲状腺癌根治术后并发症的影响。方法:选取我院2019年11月—2023年2月期间收治的312例甲状腺癌患者作为研究对象,均接受甲状腺全部切除加淋巴结清扫术,通过随机数字表法将其分成观察组202例和对照组110例。观察组在手术中使用纳米炭混悬注射液联合聚氨基葡萄糖羧酸钠医用生物胶体液,对照组在手术中不使用纳米炭混悬注射液联合聚氨基葡萄糖羧酸钠医用生物胶体液。比较两组手术指标(手术时间、术后渗血渗液量、住院时间)以及术后甲状旁腺素水平(PTH)、血钙水平。结果:观察组手术时间、住院时间短于对照组,术后渗血渗液量低于对照组(P<0.05);观察组PTH、血钙水平均高于对照组(P<0.05)。结论:在甲状腺疾病的外科手术治疗中,使用纳米炭混悬注射液联合聚氨基葡萄糖羧酸钠医用生物胶体液可缩短手术时间和住院时间、减少渗血渗液量,同时有助于保护甲状旁腺功能。Objective:To investigate the effect of carbon nanoparticles suspension injection and polyglucosamine sodium carboxylate medical biocolloid liquid on postoperative complications of radical thyroidectomy.Methods:A total of 312 patients with thyroid cancer admitted to our hospital from November 2019 to February 2023 were selected as the research objects.All patients underwent total thyroidectomy and lymph node dissection.They were divided into observation group(202 patients)and control group(110 patients)by random number table method.The observation group used carbon nanoparticles suspension injection and polyglucosamine sodium carboxylate medical biocolloid liquid,while the control group did not use carbon nanoparticles suspension injection and polyglucosamine sodium carboxylate medical biocolloid liquid during the operation.The operation indexes(operation time,postoperative bleeding volume,hospitalization time),postoperative parathyroid hormone(PTH)level and serum calcium level were compared between the two groups.Results:The operation time and hospitalization time of the observation group were shorter than those of the control group,and the amount of postoperative bleeding and exudation was lower than that of the control group(P<0.05).The levels of PTH and serum calcium in the observation group were higher than those in the control group(P<0.05).Conclusion:In the surgical treatment of thyroid diseases,the use of carbon nanoparticles suspension injection and polyglucosamine sodium carboxylate medical biocolloid liquid can shorten the operation time and hospitalization time,reduce the amount of bleeding and exudation,and help to protect parathyroid function.

关 键 词：纳米炭混悬注射液 聚氨基葡萄糖羧酸钠医用生物胶体液 甲状腺癌 

分 类 号：R736.1[医药卫生—肿瘤]