Glucocorticoid reduction induced chorea in pediatric-onset systemic lupus erythematosus:A case report  

作　　者：Yan-Qiu Xu Miao Wang Ying Zhang 

机构地区：[1]Department of Rheumatology,Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400021,China

出　　处：《World Journal of Clinical Cases》2023年第32期7872-7875,共4页世界临床病例杂志

基　　金：This study was conducted with the approval of the ethics committee of Chongqing Hospital of Traditional Chinese Medicine(approval No.2023-GAKY-KS-XYQ).The patient gave explicit informed consent to report her clinical case.

摘　　要：BACKGROUND Pediatric-onset systemic lupus erythematosus(SLE)is typically more severe than adult-onset SLE,with a higher incidence of nervous system involvement.Chorea is a relatively rare neurological complication reported in 2.4%-7%of SLE patients.In particular,chorea induced by glucocorticoid dose reduction is even rarer.Herein,we report the case of a girl with SLE,who developed chorea during the process of glucocorticoid therapy reduction.CASE SUMMARY We describe a 14-year-old girl who was diagnosed with SLE.She was treated with methylprednisolone and rituximab,and her symptoms improved.On the second day after the methylprednisolone dose was reduced according to the treatment guidelines,the patient developed chorea.Her condition improved after adjusting her glucocorticoid regimen.CONCLUSION This case is a reminder that extra attention to chorea is required in SLE patients during glucocorticoid dose reduction.

关 键 词：GLUCOCORTICOID CHOREA Pediatric systemic lupus erythematosus Case report 

分 类 号：R593.241[医药卫生—内科学] R733[医药卫生—临床医学]