氟化物防治龋齿的健康风险  

Health risks of fluoride in preventing dental caries

作　　者：陈晓雪 张振华 徐辉[1] Chen Xiaoxue;Zhang Zhenhua;Xu Hui(Department of Regenerative Medical Science,School of Pharmaceutical Sciences,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学药学院再生医学科学研究所,长春130021

出　　处：《中华地方病学杂志》2023年第11期938-941,共4页Chinese Journal of Endemiology

基　　金：国家自然科学基金(81673111)。

摘　　要：龋齿是儿童常见的慢性病之一,氟化物在龋齿的预防和治疗方面起到重要作用,但同时也存在一定的健康风险。生活中氟化物来源众多,适量摄入对人体有益,过量摄入极易引发氟斑牙、胃肠道不良反应甚至氟中毒等。本文着重梳理氟化物防治龋齿的作用机制及存在的健康风险,为合理使用氟化防龋制剂及制定水氟含量标准提供理论支持。Dental caries is one of the common chronic diseases in children.Fluoride plays a key role in the prevention and treatment of dental caries,but it also carries certain health risks.There are many sources of fluoride in daily life,and appropriate intake is beneficial to the human body.Excessive intake can easily cause dental fluorosis,gastrointestinal adverse reactions,and even fluorosis.This article focuses on the mechanism and health risks of fluoride in preventing and treating dental caries in this progress,aiming to provide theoretical support for the rational use of dental fluoride preparation and the formulation of fluoride content standard in water.

关 键 词：氟化物 龋齿 氟中毒 公共健康 

分 类 号：R788.1[医药卫生—口腔医学]