430例基底细胞癌患者临床与病理特点回顾性分析  

Retrospective analysis for clinical and histopathological features of basal cell carcinoma in 430 patients

作　　者：何萍秀 程丽芳 夏碧霞 吴忆 万川 HE Pingxiu;CHENG Lifang;XIA Bixia;WU Yi;WAN Chuan(Department of Pathology,Dermatology Hospital of Jiangxi Province,Jiangxi Provincial Clinical Research Center for Skin Diseases,Jiangxi Nanchang 330001,China;Medical College of Nanchang University,Jiangxi Nanchang 330006,China;Department of Dermatology,The First Affiliated Hospital of Nanchang University,Jiangxi Nanchang 330006,China)

机构地区：[1]江西省皮肤病专科医院病理科江西省皮肤病临床医学研究中心,江西南昌330001 [2]南昌大学医学院,江西南昌330006 [3]南昌大学第一附属医院皮肤科,江西南昌330006

出　　处：《现代肿瘤医学》2023年第23期4410-4414,共5页Journal of Modern Oncology

基　　金：国家自然科学基金项目(编号:81860484);江西省自然科学基金项目(编号:20202BABL206107)。

摘　　要：目的:通过统计和分析南昌大学第一附属医院和江西省皮肤病专科医院基底细胞癌(BCC)患者的临床及病理资料,探讨江西地区BCC的临床和病理特点,为该病的临床诊治提供参考。方法:收集、统计和分析两院2016年07月至2021年05月病理确诊为BCC患者的临床及病理资料。结果:共收集430例BCC患者,男女比例为1∶1.18,平均年龄为(67.33±12.48)岁,50岁及以上患者占90.70%,就诊年龄高峰段为60~69岁。病程10天~60年,中位数为3(0.03,60)年。430例患者确诊443块皮损,位于头面部占87.58%,其次为躯干9.48%、四肢2.26%。临床与病理诊断符合率为54.42%。病理亚型以结节型(65.01%)最多见,其次为色素型(13.32%)。结论:BCC好发于50岁以上中老年人曝光部位,部分患者病程长,临床误诊率较高,临床医生需进一步认识BCC,提高组织病理活检意识,减少误诊。Objective:To investigate the clinical and pathological characteristics of basal cell carcinoma(BCC)in Jiangxi province by statistical analysis of clinical and pathological data of patients diagnosed in Dermatology Hospital of Jiangxi Provincel.Methods:Clinical and pathological data of patients with pathologically confirmed BCC in our hospital from July 2016 to May 2021 were collected and analyzed.Results:Among 430 patients enrolled,the ratio of male to female was 1∶1.18,the mean age was(67.33±12.48)years old,and 90.70%of patients were 50 years old or above,and the peak age range was 60~69 years old.Duration of disease was 10 days to 60 years,with a median of 3 years.443 lesions were diagnosed in 430 patients,87.58%of which were located on the head and face,followed by 9.48%on the trunk and 2.26%on the limbs.The coincidence rate of clinical and pathological diagnosis was 54.42%.Nodular type(65.01%)was the most common pathological type,followed by pigment type(13.32%).Conclusion:BCC often occurs in the exposure site of middle-aged and elderly people over 50 years old.Some patients have a long course of disease and a high rate of clinical misdiagnosis.Clinicians should further understand BCC,improve the awareness of histopathological biopsy and reduce misdiagnosis.

关 键 词：基底细胞癌 临床 病理学 回顾性分析 

分 类 号：R739.5[医药卫生—肿瘤]