靶向治疗在胆道恶性肿瘤中的临床应用现状及进展  

The current status and progress of clinical application of targeted therapy in biliary tract malignant tumors

作　　者：刘千琳 张鹏飞 LIU Qianlin;ZHANG Pengfei(Cancer Center,West China Hospital,Sichuan University,Sichuan Chengdu 610041,China)

机构地区：[1]四川大学华西医院肿瘤中心,四川成都610041

出　　处：《现代肿瘤医学》2023年第23期4472-4476,共5页Journal of Modern Oncology

摘　　要：胆道恶性肿瘤严重威胁人类身体健康,手术、化疗和放疗等治疗手段临床获益有限,靶向治疗作为一种基于肿瘤特异性基因变异或蛋白质表达而开发的个体化治疗方法,药物通过特定靶标作用于肿瘤细胞产生抗肿瘤作用。本文将对胆道恶性肿瘤靶向治疗研究及进展进行简要介绍并探索未来发展方向。Biliary tract malignant tumor is a serious threat to human health.The clinical benefits of surgery,chemotherapy and radiotherapy are limited.Targeted therapy is an individualized treatment method based on tumor-specific gene mutation or protein expression.Drugs act on tumor cells through specific targets to produce anti-tumor effects.This article will briefly introduce the research and progress of targeted therapy for biliary malignant tumors and explore the future development direction.

关 键 词：胆道恶性肿瘤 治疗 靶向药物 

分 类 号：R735.8[医药卫生—肿瘤]