红外荧光显像在甲状腺癌根治手术中对甲状旁腺保护的应用价值  

Clinical application of infrared fluorescence imaging in parathyroid preservation during radical resection for thyroid cancer

作　　者：王云生[1] 薛金才[1] 王兴越 董方[2] 田尤新[1] 刘勤江[1] WANG Yunsheng;XUE Jincai;WANG Xingyue;DONG Fang;TIAN Youxin;LIU Qinjiang(Head and Neck Surgery Department,Gansu Cancer Hospital,Gansu Lanzhou 730050,China;Department of Radiotherapy,Gansu Cancer Hospital,Gansu Lanzhou 730050,China)

机构地区：[1]甘肃省肿瘤医院头颈外科,甘肃兰州730050 [2]甘肃省肿瘤医院放疗科,甘肃兰州730050

出　　处：《现代肿瘤医学》2023年第24期4548-4551,共4页Journal of Modern Oncology

基　　金：甘肃省兰州市科技发展计划项目(编号:2022-3-36)。

摘　　要：目的:探讨红外荧光显像技术在甲状癌根治手术中识别保护甲状旁腺的应用价值。方法:选取我院头颈外科2021年6月-2022年3月137例双侧甲状腺癌患者,均接受双侧甲状腺全切除+双侧中央区淋巴结清扫和(或)侧颈淋巴结清扫根治术。通过肉眼识别和红外荧光显像仪探测进行辨识甲状旁腺,分析两种识别方法的检出率、准确率。结果:137例患者共确定检出甲状旁腺491枚,对照组肉眼识别出462枚,检出率94.1%,准确率98.1%(462/471);观察组使用红外荧光显像仪探测辨识484枚,检出率98.6%,准确率97.8%(484/495)。观察组使用红外荧光显像仪检出率明显高于肉眼对照组,差异有统计学意义(χ^(2)=13.956,P<0.01);两组准确率差异无统计学意义(χ^(2)=0.115,P>0.05)。结论:甲状腺癌根治手术中应用红外荧光显像技术可明显提高甲状旁腺的检出率,更好帮助术者识别并保护甲状旁腺。Objective:To investigate the application value of infrared fluorescence imaging in the identification and protection of parathyroid glands during radical resection of thyroid cancer.Methods:137 patients with thyroid cancers enrolled from January June 2021 to March 2022 in department of head and neck surgery of our hospital were selected as research objects.All patients underwent bilateral radical thyroidectomy combined with bilateral central lymph node dissection and/or lateral neck dissection.The parathyroid gland identified by naked eye and infrared fluorescence imaging,and the detection rate and accuracy rate of the two methods were analyzed.Results:A total of 491 parathyroid glands were found in 137 patients.462(94.1%)parathyroid glands were detected by naked eye and 484(98.6%)parathyroid glands were detected by infrared fluorescence imaging(χ^(2)=13.956,P<0.01).However,the accuracy was 98.1%(462/471)by naked eye and 97.8%(484/495)by infrared fluorescence imaging(χ^(2)=0.115,P>0.05).Conclusion:Infrared fluorescence imaging can improve the detection rate of parathyroid gland in radical thyroidectomy,effectively identify and protect the parathyroid gland.

关 键 词：甲状腺癌 根治术 甲状旁腺 红外荧光显像 

分 类 号：R736.1[医药卫生—肿瘤]