毛刺征联合血管集束征在肺磨玻璃样结节良恶性鉴别诊断中的应用价值  

Application Value of Spicule Sign Combined with Vascular Cluster Sign in Differential Diagnosis of Benign and Malignant of Pulmonary Ground-glass Nodule

作　　者：廖建 阮玖根 肖琼 LIAO Jian;RUAN Jiugen;XIAO Qiong(Xinyu People's Hospital,Jiangxi Province,Xinyu 338000,China;不详)

机构地区：[1]江西省新余市人民医院,江西新余338000

出　　处：《中国医学创新》2023年第31期134-137,共4页Medical Innovation of China

摘　　要：目的:探究毛刺征联合血管集束征在肺磨玻璃样结节良恶性鉴别中的应用价值。方法:选取新余市人民医院2019年4月—2022年4月收治的113例肺磨玻璃样结节患者,入院后均进行多层螺旋CT(MSCT)检查,按照穿刺或术后病理活检结果将其分为良性组(n=45)和恶性组(n=68)。比较两组患者一般临床资料及MSCT影像学特征,以穿刺或术后病理活检结果为金标准,比较毛刺征、血管集束征单独及联合诊断恶性肺磨玻璃样结节的准确度、敏感度、特异度。结果:两组患者的性别、年龄及吸烟史比较,差异均无统计学意义(P>0.05);恶性组肿瘤家族史占比高于良性组,差异有统计学意义(P<0.05)。与良性组相比,恶性组结节高密度、形状不规则、边界粗糙、毛刺征、血管集束征、胸膜凹陷征占比均更高,病灶直径更长,差异均有统计学意义(P<0.05)。毛刺征、血管集束征单独及联合诊断的敏感度比较,差异无统计学意义(P>0.05);毛刺征、血管集束征单独及其联合诊断的特异度、准确度比较,差异均有统计学意义(P<0.05),且联合诊断的特异度、准确度均高于单一诊断(P<0.05)。结论:恶性肺磨玻璃样结节的毛刺征和血管集束征显示率均高于良性结节,其联合诊断效果良好,能有效鉴别结节的良恶性。Objective:To investigate the application value of spicule sign combined with vascular cluster sign in differential diagnosis of benign and malignant of pulmonary ground-glass nodule.Method:A total of 113 patients with pulmonary ground-glass nodule admitted to Xinyu People's Hospital from April 2019 to April 2022 were selected.Multislice spiral computed tomography(MSCT)examination was performed after admission,and they were divided into benign group(n=45)and malignant group(n=68)according to puncture or postoperative pathological biopsy result.The general clinical data and MSCT imaging features of the two groups were compared.Taking the result of puncture or postoperative pathological biopsy result as the gold standard,the accuracy,sensitivity and specificity of spicule sign and vascular cluster alone and combination in the diagnosis of malignant pulmonary ground-glass nodule were compared.Result:There were no significant differences in gender,age and smoking history between the two groups(P>0.05).The proportion of family history of tumor in the malignant group was higher than that in the benign group,the difference was statistically significant(P<0.05).Compared with the benign group,the proportions of nodule with hyperdensity,irregular shape,roughness demarcation,spicule sign,vascular cluster sign and pleural indentation sign in malignant group were higher,and the focus diameter in malignant group was longer,the differences were statistically significant(P<0.05).There was no significant difference in sensitivity between spicule sign,vascular cluster sign alone and combination diagnosis(P>0.05).There were statistically significant differences in the specificity and accuracy of spicule sign,vascular cluster sign alone and combination diagnosis(P<0.05),and the specificity and accuracy of combination diagnosis were higher than that of single diagnosis(P<0.05).Conclusion:The display rate of spicule sign and vascular cluster sign of malignant pulmonary ground-glass nodule is higher than that of benign nodule,and the co

关 键 词：肺磨玻璃样结节 多层螺旋CT 毛刺征 血管集束征 

分 类 号：R734.2[医药卫生—肿瘤]