2011-2020年福建省肿瘤登记地区甲状腺癌流行特征及变化趋势  

Epidemic characteristics and changing trends of thyroid cancer in cancer registration areas of Fujian province from 2011 to 2020

作　　者：马晶昱 相智声 林永添[1] 温烨莹 周衍[1] MA Jingyu;XIANG Zhisheng;LIN Yongtian;WEN Yeying;ZHOU Yan(Clinical Oncology School of Fujian Medical University,Fujian Cancer Hospital,Fuzhou 350014,China)

机构地区：[1]福建医科大学肿瘤临床医学院,福建省肿瘤医院,福州350014

出　　处：《实用肿瘤学杂志》2023年第4期301-307,共7页Practical Oncology Journal

摘　　要：目的分析福建省肿瘤登记地区2011—2020年甲状腺癌流行特征及变化趋势,为开展防治工作提供科学依据。方法收集整理2011—2020年福建省肿瘤登记地区发病和死亡病例。对符合评价标准的登记地区数据进行合并分析,计算甲状腺癌发病与死亡粗率、中标率、世标率、累积率(0~74岁)以及年度变化百分比(Annual percentage change,APC),人口标准化率计算采用中国2000年人口普查人口结构和Segi′s世界人口结构。结果2011—2020年福建省肿瘤登记地区甲状腺癌发病率为18.48/10万,中标率为16.16/10万,世标率为14.19/10万,累积率(0~74岁)为1.38%。甲状腺癌死亡率为0.79/10万,中标率为0.60/10万,世标率为0.59/10万,累积率(0~74岁)为0.07%。发病率在0~20岁年龄组处于较低水平,20岁以后快速上升,在50~54岁年龄组达到最高(38.67/10万)后下降。死亡率在40岁之前处于较低水平,40岁以后明显上升,在85岁以上年龄组达到最高(5.79/10万)。2011—2020年福建省肿瘤登记地区甲状腺癌的总发病率、男性发病率、女性发病率、城市地区发病率、农村地区发病率APC值分别为23.32%、25.69%、22.44%、30.05%、16.60%,中标率APC值分别为23.15%、25.96%、22.01%、30.82%、14.85%,均呈上升趋势(P<0.05)。总死亡率、城市地区死亡率及农村地区死亡率APC值分别为6.89%、8.10%、5.67%,呈上升趋势(P<0.05),而标化死亡率、男女粗死亡率及中标率、城市及农村地区标化死亡率较平稳。结论甲状腺癌是福建省主要恶性肿瘤之一,流行特征存在性别及城乡差异,发病上升趋势明显,应开展针对性的综合防治工作。Objective The objective of this study was to analyze the epidemic characteristics and changing trends of thyroid cancer in cancer registration areas of Fujian province from 2011 to 2020,and provide a scientific basis for the prevention and control work.Methods The incidence and death cases were collected and organized in the cancer registration area of Fujian province from 2011 to 2020.The data were combined and analyzed in the registered areas that met the evaluation criteria.The crude incidence and mortality,age-standardized rate(ASR)China,ASR Word,cumulative rate(0-74 years old)and annual percentage change(APC)of thyroid cancer were calculated.The population standardization rate was calculated using the population structure of the 2000 National Population census and the Segi′s world population structure.Results The incidence of thyroid cancer from 2011 to 2020 was 18.48/100,000,the ASR China was 16.16/100,000,the ASR Word was 14.19/100,000,and the cumulative rate(0-74 years old)was 1.38%.The mortality of thyroid cancer was 0.79/100,000,the ASR China was 0.60/100,000,the ASR Word was 0.59/100,000,and the cumulative rate(0-74 years old)was 0.07%.The incidence was at a low level in the age group of 0-20 years old,rising rapidly after 20 years old,and falling after reaching the highest level in the age group of 50-54 years old(38.67/100,000).The mortality of thyroid cancer was at a low level before the age of 40,but significantly increases after the age of 40,reaching its highest level in the age group over 85(5.79/100,000).The APC values of total incidence,male incidence,female incidence,urban incidence,and rural incidence of thyroid cancer from 2011 to 2020 in Fujian province were 23.32%,25.69%,22.44%,30.05%,16.60%,respectively,the APC of age-standardized rate were 23.15%,25.96%,22.01%,30.82%,and 14.85%,respectively,showing an upward trend(P<0.05).The APC values of total mortality,urban mortality and rural mortality were 6.89%,8.10%and 5.67%,respectively,showing an upward trend(P<0.05),while age-standardized m

关 键 词：甲状腺癌 发病率 死亡率 变化趋势 肿瘤登记 福建 

分 类 号：R736.1[医药卫生—肿瘤]