EUS-FNA结合沉降式液基细胞学制片技术诊断胰腺病变的价值  

The value of EUS-FNA combined with sedimentation liquid-based cytology preparation technology in thediagnosis of pancreatic lesions

作　　者：吴妍 周晋星 丁颖 席雷 戎荣 WU Yan;ZHOU Jinxing;DING Ying(Department of Pathology.Jiangsu Provirtce Hospital,Nartjing 210029,CHINA)

机构地区：[1]江苏省人民医院(南京医科大学第一附属医院)病理学部,江苏南京210029

出　　处：《江苏医药》2023年第11期1104-1107,F0002,共5页Jiangsu Medical Journal

基　　金：江苏省高校自然科学基金(21KJB320015)。

摘　　要：目的 探讨超声内镜引导细针穿刺抽吸术(EUS-FNA)结合沉降式液基细胞学(LBC)制片技术在胰腺病变诊断中的应用价值。方法 169例胰腺病变患者的EUS-FNA标本采用沉降式LBC制片技术行细胞学检查,评估EUS-FNA标本的满意率。以术后病理组织学诊断结果为金标准,分析细胞学诊断结果。结果 169例胰腺EUS-FNA标本满意率为93.5%。细胞学诊断准确率为84.2%(133/158),灵敏度为84.3%(102/121),特异度为83.8%(31/37),阳性预测值为94.4%(102/108),阴性预测值为62.0%(31/50)。结论 胰腺病变患者术前行EUS-FNA细胞学评估有较高的灵敏度和特异度。EUS-FNA细胞学检查结合沉降式LBC制片技术在胰腺病变诊断中具有较高的临床应用价值。Objective To evaluate the diagnostic value of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)combined with sedimentation liquid-based cytology(LBC)preparation technology in pancreatic lesions.Methods EUS-FNA specimens from 169 patients with pancreatic lesions were subjected to cytological examination by sedimentation LBC preparation technology to evaluate the satisfaction rate of EUS-FNA specimens.Based on the postoperative histopathological diagnosis results as the gold standard,the cytological diagnosis results were compared and analyzed.Results The satisfaction rate of 169 pancreatic EUS-FNA specimens was 93.5%.The accuracy of cytological diagnosis was 84.2%(133/158),sensitivity was 84.3%(102/121),specificity was 83.8%(31/37),positive predictive value was 94.4%(102/108),and negative predictive value was 62.0%(31/50).Conclusion Preoperative EUS-FNA cytological evaluation has high sensitivity and specificity for patients with pancreatic lesions.The combination of EUS-FNA cytological examination and sedimentation LBC preparation technology has high clinical application value in the diagnosis of pancreatic lesions.

关 键 词：胰腺病变 超声内镜引导细针穿刺抽吸术 沉降式液基细胞学 

分 类 号：R576[医药卫生—消化系统]