无痛胃肠镜检查应用二甲硅油联合聚乙二醇电解质散的肠道准备效果分析  

Analysis of the effect of intestinal preparation with dimethicone oil combined with polyethylene glycol electrolyte powder in painless gastrointestinal endoscopy

作　　者：黄艳艳 葛洪超 Huang Yanyan;Ge Hongchao(Department of Gastroenterology,Nanjing Qixia District Hospital,Nanjing 210046,China)

机构地区：[1]南京市栖霞区医院消化内科,南京210046

出　　处：《中国医师进修杂志》2023年第11期977-982,共6页Chinese Journal of Postgraduates of Medicine

基　　金：江苏大学医学临床科技发展基金项目资助(JLY20160188)。

摘　　要：目的分析无痛胃肠镜检查应用二甲硅油联合聚乙二醇电解质散的肠道准备效果。方法采用前瞻性研究的方法,纳入2020年1月至2021年6月南京市栖霞区医院收治拟行无痛胃肠镜检查患者380例,按照随机数字表法分为观察组和对照组各190例。对照组给予聚乙二醇电解质散+0.9%氯化钠做胃肠镜检查前肠道准备,观察组给予聚乙二醇电解质散+二甲硅油。比较两组肠道清洁度,祛泡效果,结肠镜检查指标,息肉、腺瘤和进展期腺瘤检出率及药物不良反应情况。结果观察组肠道清洁满意度、祛泡满意度较对照组明显增加[92.11%(175/190)比84.71%(161/190)、90.53%(172/190)比83.16%(158/190)],差异有统计学意义(P<0.05),观察组进镜时间、结肠镜检查时间较对照组明显缩短[(3.35±1.05)min比(6.02±1.68)min、(11.86±1.93)min比(15.22±2.10)min],0.9%氯化钠冲洗量明显减少[(35.68±7.64)ml比(50.34±10.30)ml],差异均有统计学意义(P<0.05),观察组<5 mm息肉检出率较对照组明显增加[15.79%(30/190)比5.79%(11/190)],腺瘤检出率较对照组明显增加[24.74%(47/190)比15.79%(30/190)],进展期腺瘤检出率较对照组明显增加[20.53%(39/190)比9.47%(18/190)],差异有统计学意义(P<0.05),观察组腹胀发生率及不良反应总发生率明显低于对照组[1.05%(2/190)比5.26%(10/190)、9.47%(18/190)比18.42%(35/190)],差异有统计学意义(P<0.05)。结论无痛胃肠镜检查应用聚乙二醇电解质散联合二甲硅油可有效提高肠道清洁度、祛泡满意度、息肉及腺瘤检出率,不良反应发生率降低,临床应用价值高。Objective To analyze the intestinal preparation effect of dimethicone oil combined with polyethylene glycol electrolyte powder in painless gastrointestinal endoscopy.Methods The study included 380 patients undergoing painless gastrointestinal endoscopy in Nanjing Qixia District Hospital from January 2020 to June 2021.They were randomly grouped into observation group and control group,with 190 patients in each group.The control group was given polyethylene glycol electrolyte powder+0.9%sodium chloride for intestinal preparation before gastrointestinal endoscopy,and the observation group was given polyethylene glycol electrolyte powder+dimethicone silicone oil.The intestinal cleanliness,antifoam effect,colonoscopy index,detection rate of polyps,adenomas and advanced adenomas,and adverse drug reactions were compared between the two groups.Results The satisfaction rates of intestinal cleaning and defoaming in the observation group were 92.11%(175/190)and 90.53%(172/190)respectively,which were obviously higher than those in the control group:84.71%(161/190)and 83.16%(158/190)(P>0.05).The entering time of colonoscopy and the time of colonoscopy inspection in the observation group were obviously shorter than those in the control group:(3.35±1.05)min vs.(6.02±1.68)min,(11.86±1.93)min vs.(15.22±2.10)min.The rinsing amount of 0.9%sodium chloride was obviously reduced:(35.68±7.64)ml vs.(50.34±10.30)ml(P<0.05).The detection rate of<5 mm polyps in the observation group was obviously higher than that in the control group:15.79%(30/190)vs.5.79%(11/190)(P<0.05).The detection rate of adenomas in the observation group was obviously higher than that in the control group:24.74%(47/190)vs.15.79%(30/190)(P<0.05).The detection rate of advanced adenomas in the observation group was obviously higher than that in the control group:20.53%(39/190)vs.9.47%(18/190)(P<0.05).The total incidences of abdominal distension and adverse reactions in the observation group were obviously lower than those in the control group:1.05%(2/190)vs.5.26%(

关 键 词：胃肠内窥镜 无痛 二甲硅油 聚乙二醇电解质散 肠道准备 

分 类 号：R57[医药卫生—消化系统]