影响青年人急性脑卒中发生的危险因素分析  

Analysis of risk factors affecting the occurrence of acute stroke in young people

作　　者：武陈陈 李慧敏 亓新凤 任伟[2] WU Chen-chen;LI Hui-min;QI Xin-feng;REN Wei(Department of Neurology,Tai’an 88th Hospital,China Rongtong Medical and Health Group,Tai’an,Shandong 271000,China)

机构地区：[1]中国融通医疗健康集团泰安八十八医院神经内科,山东泰安271000 [2]中国人民解放军第906医院疾病预防控制科

出　　处：《现代预防医学》2023年第22期4159-4163,共5页Modern Preventive Medicine

基　　金：火神山医院科研面上项目(196);泰安市科技创新发展项目(2022NS280)。

摘　　要：目的探究影响青年人急性脑卒中发生的危险因素。方法回顾性分析2019年5月至2022年5月于某三甲医院收治的122例青年急性脑卒中患者的临床资料,将其分为青年组(n=122),使用简单随机法选择同期于同一医院进行体检的109例健康青年受试者为对照组(n=109)。分析青年组与对照组受试者一般资料、合并疾病及病史差异,对影响青年人急性脑卒中发生的因素进行单因素分析,将存在差异的单因素纳入多元logistic回归分析,探究导致青年人急性脑卒中发生的危险因素。结果影响青年人急性脑卒中发生的单因素代入多因素logistic回归分析方程中发现,年龄≥35岁(OR=1.706,95%CI=1.074~2.709,P=0.024)、肥胖(OR=1.855,95%CI=1.035~3.327,P=0.039)、合并既往脑卒中史(OR=1.694,95%CI=1.183~2.425,P=0.013)、合并糖尿病(OR=1.634,95%CI=1.135~2.353,P=0.009)、合并高血压(OR=1.659,95%CI=1.170~2.351,P=0.005)、合并高血脂症(OR=1.576,95%CI=1.210~2.054,P=0.001)、存在吸烟史(OR=2.117,95%CI=1.197~3.745,P=0.010)、存在饮酒史(OR=1.960,95%CI=1.168~3.289,P=0.011)是影响青年人急性脑卒中发生的危险因素。结论年龄、肥胖、既往脑卒中史、合并糖尿病、高血压、高血脂症及存在吸烟饮酒的不良习惯均是导致青年急性脑卒中发生的危险因素,纠正青年人不良生活习惯有助于预防青年急性脑卒中发生。Objective To explore the risk factors affecting the occurrence of acute stroke in young people.Methods The clinical data of 122 young patients with acute stroke admitted to a certain Grade A hospital from May 2019 to May 2022 were retrospectively analyzed,and the patients were selected as young group(n=122),and 109 healthy young subjects who underwent physical examination in the same hospital during the same period were included in control group(n=109)by simple randomization method.The differences in general data,comorbidities and medical history were analyzed in young group and control group of subjects.Univariate analysis was carried out on the factors affecting the occurrence of acute stroke in young people,and the single factors with differences were included in multivariate Logistic regression analysis to explore the independent risk factors of acute stroke in young people.Results The single factors affecting the occurrence of acute stroke in young people were substituted into the multivariate Logistics regression analysis equation,and it was found that age≥35 years old(OR=1.706,95%CI=1.074-2.709,P=0.024),obesity(OR=1.855,95%CI=1.035-3.327,P=0.039),previous history of stroke(OR=1.694,95%CI=1.183-2.425,P=0.013),diabetes mellitus(OR=1.634,95%CI=1.135-2.353,P=0.009),hypertension(OR=1.659,95%CI=1.170-2.351,P=0.005),hyperlipidemia(OR=1.576,95%CI=1.210-2.054,P=0.001),history of smoking(OR=2.117,95%CI=1.197-3.745,P=0.010)and drinking history(OR=1.960,95%CI=1.168-3.289,P=0.011)were risk factors for acute stroke in young people.Conclusion Age,obesity,previous stroke history,diabetes mellitus,hypertension,hyperlipidemia,bad habits of smoking and drinking are risk factors leading to acute stroke in young people.Correcting bad life habits in young people is helpful to prevent acute stroke in young people.

关 键 词：急性脑卒中 青年 病因 危险因素 临床特点 预防 

分 类 号：R743.3[医药卫生—神经病学与精神病学]