颅内动脉粥样硬化性狭窄血管内支架成形术后支架再狭窄相关危险因素的研究进展  

Advances in the study of risk factors associated with in-stent restenosis after endovascular stenting for intracranial atherosclerotic stenosis

作　　者：赵新宇 朱良付 ZHAO Xinyu;ZHU Liangfu(Department of Cerebrovascular Diseases,Henan University People's Hospital,Zhengzhou,Henan Province 450003,China)

机构地区：[1]河南大学人民医院脑血管病科,河南郑州450003

出　　处：《介入放射学杂志》2023年第11期1150-1155,共6页Journal of Interventional Radiology

摘　　要：随着我国经济水平不断发展,脑卒中患病率明显上升,已跃居世界首位,且远高于欧美等发达国家。有研究显示,在亚洲由颅内动脉粥样硬化性狭窄(intracranial atherosclerotic stenosis,ICAS)所导致的脑卒中已经高达30%~50%,且有继续增高的趋势,与血管内治疗相伴的支架内再狭窄(in-stent restenosis,ISR)问题也越来越受到关注。既往研究显示,支架种类、病变血管性质、患者高危因素、患者体内相关因子水平及基因、术后药物使用等因素都可影响ISR的发生。本文拟对颅内血管ISR的危险因素进行综述。In China,with the continuous development of economic level,the incidence of cerebral stroke has also remarkably increased,which has leaped to the first place in the world and,moreover,become far higher than that in Europe,the United States and other developed countries.Studies have indicated that the incidence of stroke caused by intracranial atherosclerotic stenosis(ICAS) in Asia has been as high as 30%-50%,and it has a further increasing trend.Clinically,the endovascular therapy-related in-stent restenosis(ISR)has also attracted more and more attention from physicians.In recent years,many studies have revealed that the type of stent,the nature of the vascular lesion,the patient's high-risk factors,the levels of relevant factors and genes in patient's body,postoperative medication,and other factors can affect the occurrence of ISR.This review summarizes the risk factors for ISR of intracranial vascular stents.

关 键 词：脑卒中 颅内动脉粥样硬化 支架内再狭窄 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]