植物蛋白源诱发鱼类肠炎及修复的研究进展  

Research Progress of Plant Protein-induced Enteritis of Fish and Its Repair

作　　者：王晓艳 李宝山 孙永智 王成强 黄炳山 WANG Xiaoyan;LI Baoshan;SUN Yongzhi;WANG Chengqiang;HUANG Bingshan(Shandong Marine Resource and Environment Research Institute,Shandong Marine Fishery Feed Engineering Technology Research Center,Aquatic Animal Nutrition and Feed R&D Innovation Demonstration Platform,Shandong Key Laboratory of Marine Ecological Restoration,Yantai Key Laboratory of Quality and Safety Control and Deep Processing of Marine Food,Yantai 264006,China)

机构地区：[1]山东省海洋资源与环境研究院/山东省海水渔用饲料工程技术研究中心/水生动物营养与饲料研发创新示范平台/山东省海洋生态修复重点实验室/烟台市海珍品质量安全控制与精深加工重点实验室,山东烟台264006

出　　处：《广东海洋大学学报》2023年第6期37-46,共10页Journal of Guangdong Ocean University

基　　金：山东省重点研发计划(2021SFGC0701);山东省自然科学基金(ZR2020QC206)。

摘　　要：【目的】综述植物蛋白源引起鱼类食源性肠炎的机理,以及益生元、益生菌、功能性氨基酸对食源性肠炎的修复作用,以期为鱼类食源性肠炎的修复提供参考。【方法】以植物蛋白源含有的抗营养因子为切入点,分别阐述植物蛋白源对鱼类肠道机械屏障、化学屏障、生物屏障及免疫屏障的影响。从益生元(寡糖、多糖、酸化剂等)、益生菌及功能性氨基酸三个不同角度,分别阐述功能性饲料添加剂在鱼类食源性肠炎修复方面的有益作用。【结果与结论】物蛋白源中含有的抗营养因子会引起鱼类肠道屏障损伤;益生元、益生菌及功能性氨基酸等添加剂在缓解食源性肠炎方面具有良好效果,能通过竞争性抑制病原菌增殖、修复肠道黏膜结构、降低炎症反应及氧化应激等作用维护鱼类肠道健康。【Objective】Review the mechanism of food-induced enteritis caused by plant protein,and the repair effect of prebiotic,probiotics,and functional amino acids on food induced enteritis,in order to provide a reference for the repair of food-induced enteritis in fish.【Method】Taking the anti-nutritional factors contained in plant protein as the starting point,the effects of plant protein sources on fish intestinal mechanical barriers,chemical barriers,biological barriers and immune barriers were respectively explained.The positive effect of functional feed additiveson repair of food-induced fish enteritis were explained from the three different perspectives of prebiotics(oligosaccharides,polysaccharides,acidic agents,etc.),probiotics and functional amino acids,respectively.【Result and Conclusion】Anti-nutritional factors contained in plant proteins can cause damage to intestinal barrier of fish.Functional feed additives such as prebiotics,probiotics,and functional amino acids can alleviate food-induced enteritis.They can maintain fish intestinal health through competitive inhibitory proliferation of pathogenic bacteria,repairing intestinal mucosa structure,reducing inflammatory response and oxidation stress.

关 键 词：食源性肠炎 益生元 益生菌 功能性氨基酸 

分 类 号：S963[农业科学—水产养殖]