缺血性脑卒中患者血脂异常管理最佳证据总结  

Summary of best evidence for managing dyslipidemia in patients with ischemic stroke

作　　者：乔梦婷 陈梦霞 张静文 王梦迪 翁艳秋 陈文瑶[1,2] 于龙娟 李冬梅[3] 张玲娟[1,2] QIAO Mengting;CHEN Mengxia;ZHANG Jingwen;WANG Mengdi;WENG Yanqiu;CHEN Wenyao;YU Longjuan;LI Dongmei;ZHANG Lingjuan(Department of Clinical Nursing,The First Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200433,China;Shanghai Geriatric Nursing Management Quality Control Center,Shanghai 200433,China;Neurovascular Center,The First Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200433,China)

机构地区：[1]海军军医大学(第二军医大学)第一附属医院临床护理学教研室,上海200433 [2]上海市老年护理管理质量控制中心,上海200433 [3]海军军医大学(第二军医大学)第一附属医院脑血管病中心,上海200433

出　　处：《海军军医大学学报》2023年第12期1392-1398,共7页Academic Journal of Naval Medical University

基　　金：中国脑卒中高危人群干预适宜技术研究及推广项目(GN2020-R0004);海军军医大学(第二军医大学)“深蓝”护理科研项目(2022KYP04)。

摘　　要：目的检索并总结缺血性脑卒中患者血脂异常管理的证据。方法根据PIPOST模型明确循证问题,检索英国国家卫生与临床优化研究所等相关指南网,美国卒中协会、欧洲卒中组织等专业协会网站,以及PubMed、Cochrance Library、中国知网等数据库中关于缺血性脑卒中血脂异常管理的指南、专家共识、系统评价、证据总结,检索时限为建库至2023年9月30日。由2名研究者采用澳大利亚乔安娜布里格斯研究所(JBI)循证卫生保健中心标准等文献质量评价工具对文献进行质量评价和证据提取。结果共检索2630篇文献,通过初筛、复筛,最终纳入18篇文献,其中有13篇指南、5篇专家共识,从评估、管理目标、药物干预、非药物干预、随访管理5个方面总结出28条证据。结论缺血性脑卒中患者血脂异常管理证据总结可为临床实践提供循证依据。Objective To search and summarize the evidence of dyslipidemia management in patients with ischemic stroke.Methods According to the evidence-based problem identified by the PIPOST model,the guidelines,expert consensus,systematic review,and evidence summary about the management of dyslipidemia in ischemic stroke were retrieved in the National Institute for Health and Care Excellence and other related guide networks,American Stroke Association,European Stroke Organisation and other professional associations,and PubMed,Cochrance Library,CNKI and other databases from inception until Sep.30,2023.Two researchers evaluated the quality of the literatures and extracted the evidence according to the Australia Joanna Briggs Institute evidence-based health care center tools.Results A total of 2630 articles were retrieved,and 18 articles were included through preliminary screening and re-screening,including 13 guidelines and 5 expert consensus.Twenty-eight pieces of evidence were summarized from 5 aspects:evaluation,management objectives,drug intervention,non-drug intervention,and follow-up management.Conclusion The summary of evidence for the management of dyslipidemia in patients with ischemic stroke can provide evidence-based basis for clinical practice.

关 键 词：缺血性脑卒中 血脂异常 管理 证据总结 

分 类 号：R743.3[医药卫生—神经病学与精神病学]