中心性浆液性脉络膜视网膜病变中扁平不规则色素上皮脱离的短波长和近红外眼底自发荧光图像特征  

Characteristics of short-wavelength and near-infrared fundus autofluorescence imaging in flat irregular pigment epithelial detachment in central serous chorioretinopathy

作　　者：杨纯 周挺业 林冰 YANG Chun;ZHOU Tingye;LIN Bing(Department of Retinal,Eye Hospital of Wenzhou Medical University,Wenzhou 325000,China)

机构地区：[1]温州医科大学附属眼视光医院眼底内科,浙江温州325000

出　　处：《温州医科大学学报》2023年第12期963-968,共6页Journal of Wenzhou Medical University

摘　　要：目的:观察中心性浆液性脉络膜视网膜病变(CSCR)眼中扁平不规则色素上皮脱离(FIPED)的短波长眼底自发荧光(SW-FAF)和近红外眼底自发荧光(NIR-FAF)图像特征。方法:选取2020年3月至2021年3月温州医科大学附属眼视光医院眼底内科确诊伴有FIPED的慢性或复发性CSCR 38例38眼。使用Spectralis HRA+OCT仪行SW-FAF、NIR-FAF等多模影像检查,分析FIPED的两种FAF图像特征。结果:38例慢性或复发性CSCR眼中有20眼存在血管化FIPED,18眼存在非血管化FIPED。血管化FIPED在SW-FAF上表现为点状弱自发荧光(AF,13例,占65%),混合状弱AF(4例,占20%),点状强弱混合AF(3例,占15%);非血管化FIPED在SW-FAF上表现为点状强弱混合AF(10例,占55.6%),点状弱AF(7例,占38.9%),混合状弱AF(1例,占5.6%)。血管化FIPED在NIR-FAF上表现为融合状伴点状弱AF(16例,占80%),斑片状强弱混合AF(4例,占20%);非血管化FIPED在NIR-FAF上表现为斑片状强弱混合AF(15例,占83.3%),斑片状弱AF(3例,占16.7%)。结论:慢性或复发性CSCR患者的血管化和非血管化FIPED具有特征性SW-FAF和NIR-FAF改变,能够指导治疗和随访。Objective:To observe the short-wavelength fundus autofluorescence(SW-FAF)and near-infrared fundus autofluorescence(NIR-FAF)image characteristics of flat irregular pigment epithelial detachment(FIPED)in central serous chorioretinopathy(CSCR).Methods:A total of 38 eyes from 38 patients diagnosed with chronic or recurrent CSCR with FIPED at the Department of Retinal,Wenzhou Medical University Eye Hospital,between March 2020 and March 2021,were included for the retrospective study.SW-FAF,NIR-FAF,and other multimodal imaging examinations were performed using the Heidelberg Spectralis HRA+OCT system to analyze the FAF characteristics of FIPED.Results:Of 38 eyes with chronic or recurrent CSCR,20 eyes had vascularized FIPED and 18 eyes had non-vascularized FIPED.Vascularized FIPED showed punctate hypoautofluoresence(65%,13/20),mixed hypoautofluoresence(20%,4/20),and punctate mixed autofluorescence(15%,3/20)on SW-FAF.Non-vascularized FIPED exhibited punctate mixed autofluorescence(55.6%,10/18),punctate hypoautofluoresence(38.9%,7/18),and mixed hypoautofluoresence(5.6%,1/18)on SW-FAF.Vascularized FIPED showed fused with punctate hypoautofluoresence(80%,16/20)and patchy mixed autofluorescence(20%,4/20)on NIR-FAF.Non-vascularized FIPED demonstrated patchy mixed autofluorescence(83.3%,15/18)and patchy hypoautofluoresence(16.7%,3/18)on NIR-FAF.Conclusion:Vascularized and non-vascularized FIPED in patients with chronic or recurrent CSCR exhibit characteristic SW-FAF and NIR-FAF changes,which can guide treatment and follow-up.

关 键 词：中心性浆液性脉络膜视网膜病变 扁平不规则色素上皮脱离 脉络膜新生血管 短波长眼底自发荧光 近红外眼底自发荧光 黑色素 

分 类 号：R774.5[医药卫生—眼科]