零回波时间3.0T MRI用于检出肺癌结节  

Zero echo time 3.0T MRI for detecting lung cancer nodules

作　　者：王晓艳[1] 张焱[1] 程敬亮[1] 汪凯宇 胡瑛[1] 王岸飞[1] 宋曼丽 王文豪 WANG Xiaoyan;ZHANG Yan;CHENG Jingliang;WANG Kaiyu;HU Ying;WANG Anfei;SONG Manli;WANG Wenhao(Department of Magnetic Resonance,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;MR Research Center,GE Healthcare,Beijing 100176,China)

机构地区：[1]郑州大学第一附属医院核磁共振科,河南郑州450052 [2]GE医疗MR科研中心(中国),北京100176

出　　处：《中国介入影像与治疗学》2023年第12期740-744,共5页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的观察零回波时间(ZTE)3.0T MRI检出肺癌结节的价值。方法前瞻性纳入126例肺癌患者(共176个肺结节),以3.0T MR仪行肺部轴位ZTE成像和常规序列成像,包括T1容积内插屏气检查(VIBE)、T2刀锋序列(BLADE)及T2半傅里叶采集单次激发快速自旋回波(HASTE)序列扫描;分析ZTE MRI与CT显示肺结节特征的一致性,观察以不同MR序列检出肺结节的敏感度。结果176个肺结节中,ZTE MRI检出140个、漏诊36个。ZTE MRI与CT显示肺结节最大径及其实性部分最大径的一致性均好(ICC=0.954、0.943,P均<0.001)且差异较小,显示气管血管束、胸膜凹陷及内部支气管充气征的一致性均好(Kappa=0.894、0.912、0.917),显示结节类型及形状的一致性中等(Kappa=0.661、0.501)。ZTE MRI检出肺结节的敏感度均高于其他单独MR序列(P均<0.05);ZTE与T2-BLADE组合的敏感度均高于其他序列组合(P均<0.05)。结论ZTE 3.0T MRI检出肺癌结节的效能较好,优于常规MR序列;与T2-BLADE联合可进一步提高其敏感度。Objective To observe the value of zero echo time(ZTE)3.0T MRI for detecting lung cancer nodules.Methods Totally 126 lung cancer patients(176 lung nodules)were prospectively enrolled and underwent 3.0T MR axial lung scanning,including T1-volumetric interpolated breath-hold examination(VIBE),T2-BLADE,T2-half-Fourier acquisition single-shot turbo spin-echo(HASTE)and ZTE sequences.The consistency between ZTE MRI and previous CT for displaying characteristics of pulmonary nodules was analyzed,and the sensitivity of different MR sequences for detecting pulmonary nodules were observed.Results Among 176 pulmonary nodules showed on CT,ZTE MRI detected 140 and missed 36 ones.The consistency between ZTE MRI and CT for displaying the maximum diameter and actual maximum diameter of pulmonary nodules were both good(ICC=0.954,0.943,both P<0.001),and the difference between ZTE MRI and CT was small.The consistency between ZTE MRI and CT for displaying tracheal vascular bundles,pleural indentation and internal bronchial inflation signs were all good(Kappa=0.894,0.912,0.917),while for displaying the type and shape of nodules were both moderate(Kappa=0.661,0.501).The sensitivity of ZTE MRI for detecting pulmonary nodules was higher than that of other individual MR sequences(all P<0.05),of combination of ZTE and T2 BLADE was higher than that of other sequence combinations(all P<0.05).Conclusion ZTE 3.0T MRI could be used to detect lung cancer nodules,which was superior to conventional MRI.Combination of ZTE 3.0T MRI with T2-BLADE could improve the sensitivity for detecting pulmonary nodules.

关 键 词：肺肿瘤 磁共振成像 回波时间 体层摄影术 X线计算机 前瞻性研究 

分 类 号：R734.2[医药卫生—肿瘤] R445.2[医药卫生—临床医学]