外阴孤立性纤维性肿瘤一例并文献复习  

Vulvar Solitary Fibrous Tumor:A Case Report and Literature Review

作　　者：周畅 段华[1] 郭银树[1] 何春燕 ZHOU Chang;DUAN Hua;GUO Yin-shu;HE Chun-yan(Gynecology Minimally Invasive Center,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing 100006,China;Department of Pathology,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing 100006,China)

机构地区：[1]首都医科大学附属北京妇产医院/北京妇幼保健院妇科微创中心,100006 [2]首都医科大学附属北京妇产医院/北京妇幼保健院病理科,100006

出　　处：《国际妇产科学杂志》2023年第6期660-664,共5页Journal of International Obstetrics and Gynecology

摘　　要：孤立性纤维性肿瘤(solitary fibrous tumor,SFT)是一种少见的间叶源性肿瘤,外阴SFT尤为罕见。外阴SFT患者通常以外阴无痛性肿物就诊,其发病机制及病因未明。由于发病率极低,妇科医生普遍对其认识不足,易造成漏诊和误诊。报告1例33岁原发性外阴SFT病例资料,患者因自觉外阴不适1年收入院,彩色多普勒超声提示右侧大阴唇皮下实性肿物,行高能量超脉冲二氧化碳激光外阴肿物切除治疗,术中见肿物呈椭圆形,大小约为3.0 cm×2.5 cm,与周围组织界限清楚,未达肌层,经病理、免疫组织化学及Demicco模型风险分层诊断为外阴SFT(低度恶性潜能),建议密切随诊。术后随访6个月,未见肿瘤复发和转移。Solitary fibrous tumor(SFT)is a rare mesenchymal tumor,and vulvar SFT is particularly rare.Patients with vulvar SFT usually present with a painless mass in the vulva,the pathogenesis and etiology of which are unknown.Due to the extremely low incidence,gynecologists generally have insufficient understanding of it,which is easy to cause missed diagnoses and misdiagnoses.The data of a 33-year-old case of primary vulvar SFT were reported.The patient was admitted to the hospital due to self-conscious vulvar discomfort for 1 year,and color Doppler ultrasound showed a solid subcutaneous mass in the right labia majora.High-energy ultra pulse carbon dioxide laser vulvar mass resection was performed,and the mass appeared oval during the operation,with a size of about 3.0 cm×2.5 cm,with clear boundaries to surrounding tissues,and did not involve the muscular layer.It was diagnosed as vulvar SFT(low malignant potential)by pathology,immunohistochemistry and Demicco model risk stratification,and close follow-up was recommended.After 6 months of postoperative follow-up,no tumor recurrence or metastasis was seen.

关 键 词：外阴孤立性纤维瘤 外阴肿瘤 二氧化碳 激光 气体 免疫组织化学 诊断 

分 类 号：R737.35[医药卫生—肿瘤]