卡度尼利单抗单药及联合化疗治疗复发性宫颈癌一例  

A Case of Recurrent Cervical Cancer Treated with Cadonilimab Monotherapy and Combination Chemotherapy

作　　者：石蕊 冯淑娴 马薇[1] 张宗翠 SHI Rui;FENG Shu-xian;MA Wei;ZHANG Zong-cui(Department of Medicine,Northwest Minzu University,Lanzhou 730030,China;Department of Gynecology,The 940th Hospital of Joint Logistics Support Force of People′s Liberation Army,Lanzhou 730050,China)

机构地区：[1]西北民族大学医学部,兰州730030 [2]中国人民解放军联勤保障部队第九四〇医院妇科

出　　处：《国际妇产科学杂志》2023年第6期665-667,共3页Journal of International Obstetrics and Gynecology

基　　金：中央高校基本科研业务费项目(31920200001)。

摘　　要：宫颈癌的发病率高居妇科恶性肿瘤之首,目前手术仍然是早期宫颈癌有效的治疗方法。但宫颈癌具有较高的复发率和远处转移能力,晚期预后差,治疗选择有限。报告1例宫颈癌根治术和放化疗联合治疗后仍复发,出现膀胱阴道瘘和直肠阴道瘘并发严重感染的患者,经卡度尼利单抗单药及联合化疗治疗取得了生存获益,旨在为复发性宫颈癌的治疗提供新思路。The incidence rate of cervical cancer is the highest among gynecological malignancies.At present,surgery is still an effective treatment for early-stage cervical cancer,but cervical cancer has a high recurrence rate and distant metastasis,poor prognosis in advanced stages,and limited treatment options.This article focuses on a case with recurrence of cervical cancer despite radical hysterectomy and combined chemotherapy and radiotherapy,who developed vesicovaginal fistula and rectovaginal fistula with severe infection,and achieved a survival benefit by treatment with cadonilimab monotherapy and combination chemotherapy.It aims to provide new ideas for the treatment of recurrent cervical cancer.

关 键 词：宫颈肿瘤 免疫疗法 卡度尼利单抗 复发 药物疗法 药物疗法 联合 

分 类 号：R737.33[医药卫生—肿瘤]