两种不同术式治疗Ⅰ期子宫内膜癌的临床研究  

Clinical study of two different surgical methods in the treatment of stageⅠendometrial carcinoma

作　　者：王子珊 郑杰 张利军 WANG Zishan;ZHENG Jie;ZHANG Lijun(Department of Obstetrics and Gynecology,the Third People's Hospital of Liaoyang,Liaoyang,Liaoning,111000,China)

机构地区：[1]辽阳市第三人民医院妇产科,辽宁辽阳111000

出　　处：《当代医学》2023年第15期65-68,共4页Contemporary Medicine

摘　　要：目的探讨两种不同术式治疗Ⅰ期子宫内膜癌的临床疗效。方法选取2012年2月至2016年2月本院收治的80例Ⅰ期子宫内膜癌患者为研究对象,按照随机数字表法分为观察组与对照组,每组40例。观察组予以单纯全子宫双附件切除术治疗,对照组予以全子宫双附件切除联合盆腔腹主动脉旁淋巴结清扫术治疗,比较两组手术时间、术中出血量、并发症发生率、围手术期生命质量评分及复发率。结果观察组术中出血量少于对照组,手术时间短于对照组,差异有统计学意义(P<0.05)。术后,两组生理、社会家庭、情感、功能评分均低于术前,且观察组生理、功能评分均低于对照组,差异有统计学意义(P<0.05),两组社会家庭、情感评分比较差异无统计学意义。两组尿潴留、肠梗阻、下肢静脉血栓发生率比较差异无统计学意义;观察组淋巴囊肿、泌尿系感染、下肢水肿发生率均低于对照组,差异有统计学意义(P<0.05)。两组复发率比较差异无统计学意义。结论与全子宫双附件切除联合盆腔腹主动脉旁淋巴结清扫术相比,单纯全子宫双附件切除术的切除范围较小,对患者造成的损伤较小,术中出血明显减少,手术时间缩短,术后并发症发生风险降低,有助于患者术后恢复,提高其生命质量,故临床应避免过度治疗而增加手术风险。Objective To investigate the clinical efficacy of two different surgical methods in the treatment of stageⅠendometrial cancer.Methods 80 patients with stageⅠendometrial cancer in our hospital from February 2012 to February 2016 were selected as the research subjects,they were divided into the observation group and the control group by the random number table method,with 40 cases in each group.The observation group was treated with total hysterectomy and bilateral salpingo-oophorectomy,while the control group was treated with total hysterectomy and bilateral salpingo-oophorectomy combined with pelvic para-aortic lymph node dissection,the operation time,intraoperative blood loss,complication rate,perioperative quality of life score and recurrence rate were compared between the two groups.Results The intraoperative blood loss in the observation group was lower than that in the control group,and the operation time was shorter than that in the control group,the differences were statistically significant(P<0.05).After operation,the scores of physiology,social family,emotion and function in the two groups were lower than those before operation,and the scores of physiology and function in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05),there were no significant differences in social family and emotion scores between the two groups.There was no significant difference in the incidence of urinary retention,intestinal obstruction and lower extremity venous thrombosis between the two groups;the incidence of lymphocyst,urinary tract infection and lower extremity edema in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in recurrence rate between the two groups.Conclusion Compared with total hysterectomy and bilateral salpingo-oophorectomy combined with pelvic para-aortic lymph node dissection,total hysterectomy and bilateral salpingo-oophorectom

关 键 词：Ⅰ期子宫内膜癌 单纯全子宫双附件切除术 盆腔腹主动脉旁淋巴结清扫术 

分 类 号：R737.33[医药卫生—肿瘤]