环乳晕切口手术治疗乳腺纤维瘤的临床疗效及对乳晕区感觉神经功能和瘢痕愈合的影响  

Clinical efficacy of circumferential areola incision surgery in the treatment of breast fibroma and effect on sensory nerve function and scar healing in the areola area

作　　者：张文杰 ZHANGWenjie(Second Department of Surgery,Mudan Central Hospital of Heze City,Heze,Shandong,274000,China)

机构地区：[1]菏泽市牡丹区中心医院外二科,山东菏泽274000

出　　处：《当代医学》2023年第15期149-151,共3页Contemporary Medicine

摘　　要：目的探讨环乳晕切口手术治疗乳腺纤维瘤的临床疗效及对乳晕区感觉神经功能和瘢痕愈合的影响。方法选取2020年4月至2021年4月于菏泽市牡丹区中心医院治疗87例乳腺纤维瘤患者作为研究对象,根据手术方案不同分为对照组(n=43)与观察组(n=44)。对照组给予传统开放式切口手术治疗,观察组给予环乳晕切口手术治疗,比较两组乳晕边缘切口瘢痕直径、温哥华瘢痕量表(VSS)评分和治疗前后基质金属蛋白酶-9、血管内皮生长因子水平及乳晕区感觉神经功能。结果观察组乳晕边缘切口瘢痕直径短于照组,VSS评分低于组照组,差异有统计学意义(P<0.05)。治疗后,两组基质金属蛋白酶-9、血管内皮生长因子水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。术后6个月,观察组乳晕区感觉神经功能评级优于对照组,差异有统计学意义(P<0.05)。结论环乳晕切口手术治疗乳腺纤维瘤患者可缩短手术切口瘢痕,有助于其瘢痕愈合,可有效改善乳晕区感觉神经功能,减少手术应激反应,值得临床推广应用。Objective To investigate the clinical efficacy of circumferential areola incision surgery in the treatment of breast fibroma and effect on sensory nerve function and scar healing in the areola area.Methods 87 patients with breast fibroma treated in Mudan Central Hospital of Heze City from April 2020 to April 2021 were selected as the study subjects,and they were divided into the control group(n=43)and the observation group(n=44)according to the different surgical programs.The control group was treated with traditional open incision surgery,and the observation group was treated with circumferential areola incision surgery,the scar diameter of areola margin incision,Vancouver scar scale(VSS)score,matrix metalloproteinase-9,vascular endothelial growth factor levels before and after treatment and sensory nerve function in areola area were compared between the two groups.Results The scar diameter of the areola edge incision in the observation group was shorter than that in the control group,and the VSS score was lower than that in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of matrix metalloproteinase-9 and vascular endothelial growth factor in 2 groups were lower than before treatment,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).After 6 months of surgery,the sensory nerve function rating of the areola area in the observation group was better than that in the control group,the difference was statistically significant(P<0.05).Conclusion The surgical treatment of breast fibroma patients with areola incision can shorten the scar of the surgical incision,help the scar healing,effectively improve the sensory nerve function in the areola area,and reduce the surgical stress response,and is worthy of clinical promotion and application.

关 键 词：环乳晕切口手术 乳腺纤维瘤 瘢痕愈合 乳晕区感觉神经功能 

分 类 号：R737.9[医药卫生—肿瘤]