围绝经期与代谢综合征的关联性研究  

Study on the correlation between perimenopause and metabolic syndrome

作　　者：冯嘉楠 陶丽新[1] 郭秀花 陈硕[2] 康晓平 FENG Jianan;TAO Lixin;GUO Xiuhua;CHEN Shuo;KANG Xiaoping(School of Public Health,Capital Medical University,Beijing100069,China;Department of Information,Beijing Medical Examination Center,Beijing100077,China;Office,Beijing Xiaotangshan Hospital,Beijing102211,China)

机构地区：[1]首都医科大学公共卫生学院,北京100069 [2]北京市体检中心信息科,北京100077 [3]北京市小汤山医院办公室,北京102211

出　　处：《中国医药导报》2023年第30期104-107,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81872708)。

摘　　要：目的探讨围绝经期与代谢综合征(MS)的关联性。方法采用横断面研究的方法,选取2014—2017年北京小汤山医院40~60岁女性的体检数据,收集受试者的临床资料,采用logistic回归模型分析围绝经期女性MS影响因素。结果不同年龄、学历情况、工作压力、饮食口味、吃饭速度、绝经情况MS患病率比较,差异有统计学意义(P<0.05)。未纳入绝经情况的女性MS患病危险因素分析显示,年龄>46~53岁女性MS患病情况是40~46岁的1.784倍,年龄>53~60岁女性MS患病情况是40~46岁的2.631倍;最高学历为大专/本科女性MS患病情况是初中及以下的0.539倍,最高学历是研究生及以上女性MS患病情况是初中及以下的0.262倍;吃早饭次数为3~5次/周女性MS患病情况是<3次/周的0.322倍;吃饭速度快的女性MS患病情况是细嚼慢咽的2.701倍。未纳入年龄因素的女性MS患病危险因素分析显示,最高学历为研究生及以上女性MS患病情况是初中及以下的0.141倍;吃饭速度中等女性MS患病情况是细嚼慢咽的2.483倍,吃饭速度快的女性MS患病情况是细嚼慢咽的3.572倍;已绝经女性MS患病情况是未绝经的1.808倍。结论女性围绝经期与MS的发生具有相关性,围绝经期女性应提早防治MS提高绝经前后的生活质量。Objective To explore the correlation between perimenopause and metabolic syndrome(MS).Methods Using the method of cross-sectional study,the data of physical examination of women aged 40-60 years in Beijing Xiaotangshan Hospital from 2014 to 2017 were selected.The clinical data of subjects were collected and the influencing factors of MS in perimenopausal women were analyzed by logistic regression model.Results There were statistically significant differences in the prevalence of MS among different ages,educational background,working pressure,dietary taste,eating speed,and menopausal conditions(P<0.05).Analysis of risk factors for MS in women not included in menopause showed that the prevalence of MS in women aged>46-53 was 1.784 times that of women aged 40-46,and the prevalence of MS in women aged>53-60 was 2.631 times that of women aged 40-46;the prevalence of MS in women with the highest education of junior college or undergraduate was 0.539 times that of junior high school or below,and the prevalence of MS in women with the highest education of graduate school or above was 0.262 times that of junior high school or below;women who ate breakfast three to five times a week were 0.322 times more likely to have MS than women who ate breakfast three times a week;women who ate fast were 2.701 times more likely to have MS than those who ate slowly.Analysis of risk factors for MS in women without age factors showed that the prevalence of MS in women with the highest education of graduate school or above was 0.141 times that of junior high school or below;the prevalence of MS in women with moderate eating speed was 2.483 times that of eating slowly,and that in women with fast eating speed was 3.572 times that of eating slowly;the incidence of MS in postmenopausal women was 1.808 times that of pre-menopausal women.Conclusion Perimenopause is related to the occurrence of MS.Perimenopausal women should prevent and treat MS in advance to improve the quality of life before and after menopause.

关 键 词：代谢综合征 围绝经期 流行病学 LOGISTIC回归 

分 类 号：R589[医药卫生—内分泌]