云南红药胶囊治疗气滞血瘀、气阴两虚证视网膜静脉阻塞患者眼底的效果  

Effect of Yunnan Hongyao Capsules in the treatment of patients with retinal vein obstruction of qi stagnation and blood stasis and Qi-Yin deficiency syndrome

作　　者：史银娟 吴虎强 李苑碧 李文君 李月明 夏泽梅 SHI Yinjuan;WU Huqiang;LI Yuanbi;LI Wenjun;LI Yueming;XIA Zemei(Department of Ophthalmology,Anning First People’s Hospital,Yunnan Province,Anning650300,China;Department of Ophthalmology,Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan Province,Kunming650000,China)

机构地区：[1]云南省安宁市第一人民医院眼科,云南安宁650300 [2]云南省中医医院眼科,云南昆明650000

出　　处：《中国医药导报》2023年第30期130-133,共4页China Medical Herald

基　　金：云南省科技厅科技计划项目[2018FF001(-060)]。

摘　　要：目的探究云南红药胶囊治疗气滞血瘀、气阴两虚证视网膜静脉阻塞患者眼底的效果。方法2019年6月至2020年5月云南省中医医院眼科收治的50例视网膜静脉阻塞眼底出血住院患者,按照随机数字表法分为对照组、试验组,每组25例。对照组、试验组分别实施羟苯磺酸钙、联合云南红药胶囊治疗。比较两组视力水平、眼底情况、黄斑水肿、整体治疗效果、凝血功能指标。结果治疗后,两组视力水平高于治疗前,且实验组高于对照组,差异有统计学意义(P<0.05)。试验组眼底改善情况优于对照组,差异有统计学意义(P<0.05)。治疗后,两组黄斑水肿低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.05)。试验组整体治疗效果优于对照组,差异有统计学意义(P<0.05)。治疗后,两组凝血酶时间、活化部分凝血活酶时间、凝血酶原时间短于治疗前,纤维蛋白原低于治疗前,且试验组凝血酶时间、活化部分凝血活酶时间、凝血酶原时间长于对照组,纤维蛋白原高于对照组,差异有统计学意义(P<0.05)。结论在视网膜静脉阻塞眼底出血中,应用云南红药胶囊联合羟苯磺酸钙治疗可以有效改善视力水平、眼底情况及凝血功能指标,进而减少黄斑中心凹厚度,提升治疗效果。Objective To explore the effect of Yunnan Hongyao Capsules in treating patients with retinal vein obstruction of Qi stagnation and blood stasis and Qi-Yin deficiency syndrome.Methods Fifty hospitalized patients with retinal vein occlusion and fundus hemorrhage admitted to the Department of Ophthalmology,Yunnan Provincial Hospital of Traditional Chinese Medicine from June 2019 to May 2020 were divided into control group and experimental group according to random number table method,with 25 cases in each group.The control group and the experimental group were treated with Calcium Hydroxybenzene Sulfonate and Yunnan Hongyao Capsules respectively.The visual acuity level,fundus condition,macular edema,overall treatment effect,and coagulation function indexes were compared between the two groups.Results After treatment,the visual acuity level of the two groups were higher than those before treatment,while that of the experimental group was higher than that of the control group,and the differences were statistically significant(P<0.05).The improvement of fundus in experimental group was better than that in control group,and the difference was statistically significant(P<0.05).After treatment,macular edema in the two groups were lower than before treatment,while that of the experimental group was lower than that of the control group,and the differences were statistically significant(P<0.05).The overall treatment effect of the experimental group was better than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the thrombin time,activated partial thrombin time,and prothrombin time of the two groups were shorter than before treatment,and the fibrinogen time was lower than before treatment,while the thrombin time,activated partial thrombin time,and prothrombin time of the experimental group were longer than those of the control group,and the fibrinogen time of the experimental group was higher than that of the control group,and the differences were statistically significant(P<

关 键 词：云南红药胶囊 羟苯磺酸钙 视网膜静脉阻塞 止血效果 凝血功能 黄斑中心凹厚度 

分 类 号：R774.1[医药卫生—眼科]