腹腔镜前列腺切除术中保留尿道床对前列腺癌患者术后早期尿控及5年生化复发率的影响  

Early urinary control and long-term effect of retroperitoneal retroperitoneal urethral bed reserved prostatectomy in patients with prostate cancer

作　　者：黄丽芳[1] 何昌莹 林小珍 覃天资 韦桂源 HUANG Li-fang;HE Chang-ying;LIN Xiao-zhen(Department of Urology,Affiliated Hospital of Youjiang Medical University for Nationalities,Baise Guangxi 533000,China)

机构地区：[1]右江民族医学院附属医院泌尿外科,广西百色533000 [2]右江民族医学院护理学院,广西百色533000

出　　处：《临床和实验医学杂志》2023年第22期2405-2408,共4页Journal of Clinical and Experimental Medicine

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(编号:Z20200294)。

摘　　要：目的探究腹腔镜前列腺切除术中保留尿道床对前列腺癌患者术后早期尿控及5年生化复发率的影响。方法回顾性分析2016年5月至2018年5月右江民族医学院附属医院收治的200例前列腺癌患者的临床资料,全部患者均行腹腔镜下耻骨后腹膜外前列腺切除术,按术中是否保留尿道床分为对照组(n=84,未保留)与研究组(n=116,保留)。比较两组手术时间、住院时间、术中出血量、引流管留置时间、术后并发症、术后早期尿控及远期疗效。结果研究组与对照组手术时间、住院时间及引流管留置时间比较,差异均无统计学意义(P>0.05);研究组的术中出血量为(237.52±62.45)mL,少于对照组[(256.13±57.24)mL],差异有统计学意义(P<0.05)。研究组并发症总发生率为11.21%(13/116),与对照组17.86%(15/84)比较,差异无统计学意义(P>0.05)。研究组术后3个月尿控率为87.93%(102/116),高于对照组[65.48%(55/84)],差异有统计学意义(P<0.05);研究组术后6、10个月尿控率分别为93.10%(108/116)、96.55%(112/116),与对照组[88.10%(74/84)、92.86%(78/84)]比较,差异均无统计学意义(P>0.05)。研究组切缘阳性率及术后5年生化复发率分别为17.24%(20/116)、19.83%(23/116),与对照组[14.29%(12/84)、29.76%(25/84)]比较,差异均无统计学意义(P>0.05)。结论前列腺癌患者腹腔镜下耻骨后腹膜外保留尿道床前列腺切除术后早期尿控效果较好,且术后5年生化复发率较低。Objective To explore the early urinary control and long-term efficacy of retroperitoneal retroperitoneal urethral bed reserved prostatectomy in patients with prostate cancer.Methods Clinical data of 200 patients with prostate cancer admitted to Affiliated Hospital of Youjiang Medical University for Nationalities from May 2016 to May 2018 were retrospectively analyzed.All patients underwent retroperitoneal peritoneal prostatectomy and were divided into control group(n=84,not reserved)and study group(n=116,reserved)according to whether the urethral bed was preserved during the operation.The operative indexes,postoperative complications,early postoperative urinary control and long-term efficacy were compared between the two groups.Results There were no statistically significant differences in operation time,hospital stay and drainage indwelling time between the two groups(P>0.05).The intraoperative blood loss in the study group was(237.52±62.45)mL,which was lower than that in the control group[(256.13±57.24)mL],the difference was statistically significant(P<0.05).The total incidence of complications in the study group was 11.21%(13/116),and there was no statistically significant difference compared to the control group 17.86%(15/84)(P>0.05).The 3-month postoperative urinary control rate in the study group was 87.93%(102/116),which was higher than that in the control group[65.48%(55/84)],the difference was statistically significant(P<0.05).The postoperative urinary control rates of the study group at 6 and 10 months were 93.10%(108/116)and 96.55%(112/116),respectively,compared with the control group[88.10%(74/84)and 92.86%(78/84)],there were no statistically significant differences(P>0.05).There were no statistically significant differences in the positive rate of incisal margin and the biochemical recurrence rate 5 years after surgery between the two groups(P>0.05).Conclusion The effect of early urinary control after retroperitoneal prostatectomy with urethral bed preservation is better in patients with prostate c

关 键 词：腹腔镜 前列腺切除术 前列腺癌 尿道床 尿控 

分 类 号：R737.25[医药卫生—肿瘤]