Carnoy's液在颌骨囊性病变辅助治疗中的应用  

Application of Carnoy's Solution in Adjuvant Treatment of Jaw Cystic Lesions:A Review

作　　者：满其文 王含琪 MAN Qiwen;WANG Hanqi(Department of Oral and Maxillofacial Surgery,Hospital of Stomatology,Wuhan University,Wuhan 430079,China;State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University,Wuhan 430079,China)

机构地区：[1]武汉大学口腔医院口腔颌面外科,湖北武汉430079 [2]武汉大学口腔医学院口腔基础医学省部共建国家重点实验室培育基地和口腔生物医学教育部重点实验室,湖北武汉430079

出　　处：《口腔医学研究》2023年第12期1046-1049,共4页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:82001066)。

摘　　要：牙源性角化囊肿和单囊型成釉细胞瘤是常见的颌骨良性病变,具有较强的局部侵袭性。好发于青少年,且多见于颌骨后分或升支部位。单纯的病变刮治或开窗减压术处理后,有较高的术后复发率,而手术联合辅助治疗例如物理或化学处理可显著降低其复发率。Carnoy's液是临床上应用较早的化学固定剂,在颌骨囊性病变尤其是牙源性角化囊肿辅助治疗中的作用已得到广泛验证,但目前部分临床医生对Carnoy's液临床应用的适应证和安全性仍存在顾虑。本综述回顾Carnoy's液及其改良制剂的作用原理、临床应用的有效性及安全性问题。Odontogenic keratocysts and unicystic ameloblastomas are common benign lesions of the jaw but are locally aggressive.The above-mentioned lesions are all prone to occur in adolescents,and are more common in the posterior part of the jaw or the ascending ramus.Due to the limited field of view in the operation area and the high invasion ability of the lesion itself,there is often a high postoperative recurrence rate after simple curettage or decompression,and surgical methods combined with adjuvant therapy such as physical or chemical treatment can significantly reduce the recurrence.Carnoy's solution is a chemical fixative used early in clinical practice.Carnoy's solution has been widely verified in the adjuvant treatment of cystic lesions of the jaw,especially odontogenic keratocyst.However,some clinicians still have concerns about the indications and safety of the clinical application of Carnoy's solution.This review introduces the principle,effectiveness,and safety of Carnoy's solution and its modified patterns in treatment of jaw cystic lesions.

关 键 词：Carnoy's液 牙源性角化囊肿 单囊成釉细胞瘤 复发 辅助治疗 

分 类 号：R782[医药卫生—口腔医学]