超声剪切波弹性成像和磁共振弹性成像对非酒精性脂肪性肝病肝脂肪变性分级的诊断性能比较  

Evaluation of ultrasonic shear wave vs.magnetic resonance elastography in diagnosing nonalcoholic fatty liver disease

作　　者：陈坛寿 缪铃梅 施增金 CHEN Tan-shou;MIU Ling-mei;SHI Zeng-jin(Department of Ultrasound,Ningde Municipal Hospital of Ningde Normal University,Fujian 352100,China;Emergency Department,Ningde Municipal Hospital of Ningde Normal University,Fujian 352100,China;Ningde Medical Fund Guarantee Center,Fujian 352100,China)

机构地区：[1]宁德师范学院附属宁德市医院超声科,福建352100 [2]宁德师范学院附属宁德市医院急诊科,福建352100 [3]宁德市医疗基金保障中心

出　　处：《肝脏》2023年第11期1356-1358,共3页Chinese Hepatology

摘　　要：目的比较超声剪切波弹性成像(SWE)、磁共振弹性成像(MRE)对NAFLD肝脂肪变性分级的诊断性能。方法回顾性分析2019年10月至2022年4月在宁德市医院诊治的88例非酒精性脂肪性肝病患者的临床资料,依据病理检查结果进行肝脂肪变性分级。所有患者均行SWE、MRE检查,比较两种检查方法对NAFLD肝脂肪变性分级的诊断效能。结果F0、F1、F2、F3的Emean值分别为(6.34±0.65)kPa、(8.08±1.22)kPa、(10.95±1.34)kPa、(14.25±2.02)kPa,ADC值分别为(1.25±0.18)10^(-3) mm^(2)/s、(1.14±0.13)10^(-3) mm^(2)/s、(1.04±0.09)10^(-3) mm^(2)/s、(0.92±0.05)10^(-3) mm^(2)/s。随着肝脂肪变性分级的增加,Emean值逐渐升高,ADC值逐渐降低,差异有统计学意义(P<0.05)。SWE诊断不同肝脂肪变性分级的AUC分别为0.855、0.823、0.841、0.827,MRE诊断不同肝脂肪变性分级的AUC分别为0.901、0.897、0.911、0.927。结论相较于SWE,MRE诊断NAFLD肝脂肪变性分级的诊断效能更优。Objective To compare the diagnostic efficacy of ultrasonic shear wave elastography(SWE)vs.magnetic resonance elastography(MRE)for hepatic steatosis in nonalcoholic fatty liver disease(NAFLD).Methods Clinical data from 88 patients diagnosed and treated for NAFLD between October 2019 to April 2022 in our hospital were retrospectively analyzed.Liver steatosis was categorized based on pathological findings.Both SWE and MRE were used to evaluate each patients,and their diagnostic performance in grading NAFLD liver steatosis was compared.Results For various liver steatosis grades,Emean values were(6.34±0.65)kPa,(8.08±1.22)kPa,(10.95±1.34)kPa,and(14.25±2.02)kPa,while ADC values were(1.25±0.18)10^(-3) mm^(2)/s,(1.14±0.13)10^(-3) mm^(2)/s,(1.04±0.09)10^(-3) mm^(2)/s,(0.92±0.05)10^(-3) mm^(2)/s,respectively.As liver steatosis grade escalated,there was a marked increase inn the Emean value and a corresponding decline in the ADC value,with these differences being statistically significant(P<0.05).In terms of diagnostic accuracy,the area under the curve(AUC)for SWE diagnosis across different liver steatosis grades was 0.855,0.823,0.841,0.827.Conversely,for MRE diagnosis,the AUC values were 0.901,0.897,0.911,0.927.Notably,the AUC for MRE diagnosis surpassed that of SWE for all hepatic steatosis grades.Conclusion MRE is more effective than SWE in diagnosing hepatic steatosis in NAFLD.

关 键 词：非酒精性脂肪性肝病 肝脂肪变性分级 超声剪切波弹性成像 磁共振弹性成像 诊断效能 

分 类 号：R575.5[医药卫生—消化系统]