胃镜下活体组织检查与外科手术病理检查在胃癌诊断中应用价值对比  

Comparison of the Diagnostic Application Value of Gastroscopy Live Tissue Examination and Surgical Pathological Examination for Gastric Cancer

作　　者：郑秀平 卢丽花 李鑫静 ZHENG Xiuping;LU Lihua;LI Xinjing(Longyan First Hospital,Fujian Province,Longyan 364000,China)

机构地区：[1]福建省龙岩市第一医院,福建龙岩364000

出　　处：《中国医学创新》2023年第34期171-174,共4页Medical Innovation of China

摘　　要：目的:探究胃镜下活体组织检查、外科手术病理检查在胃癌内的诊断价值。方法:选取2020年1月—2021年12月龙岩市第一医院收治的329例疑似胃癌患者,对所有患者均施以胃镜下活体组织检查与外科手术病理检查,对比两者诊断胃癌的效能。结果:329例疑似胃癌患者,经外科手术病理检查共检出324例胃癌,胃镜下活体组织检查共检出319例胃癌,两者诊断检出率相比,差异无统计学意义(P>0.05)。以外科手术病理检查为“金标准”,Kappa检验显示,胃镜下活体组织检查同“金标准”具有中等的一致性(Kappa=0.524,P=0.000)。两者检查各胃癌组织类型的检出率相当,差异均无统计学意义(P>0.05);胃镜下活体组织检查弥漫浸润型及分化型胃癌检出率均低于“金标准”,差异均有统计学意义(P<0.05)。结论:外科手术病理检查在胃癌检查中效果更为显著,而胃镜下活体组织检查创伤性更小,对于胃癌病变的积极预防与有效治疗意义重大,可作为术前检测胃癌的初诊方法。Objective:To explore the diagnostic value of live tissue examination under gastroscopy and surgical pathological examination in gastric cancer.Method:From January 2020 to December 2021,329 patients with suspected gastric cancer admitted to Longyan First Hospital were selected,all patients were subjected to live tissue examination under gastroscopy and surgical pathological examination,and the efficacy of both in the diagnosis of gastric cancer was compared.Result:Out of 329 suspected gastric cancer patients,a total of 324 gastric cancer cases were detected through surgical pathological examination,and 319 gastric cancer cases were detected through gastroscopy live tissue examination,there was no statistically significant difference in the diagnostic detection rate between the two methods(P>0.05).Using surgical pathological examination as the"gold standard",Kappa test showed moderate consistency between live tissue examination under gastroscopy and the"gold standard"(Kappa=0.524,P=0.000).The detection rates of each type of gastric cancer tissue examined by both methods were similar,the differences were not statistically significant(P>0.05);the detection rate of diffuse infiltrative and differentiated gastric cancer under gastroscopy were lower than those the"gold standard",the differences were statistically significant(P<0.05).Conclusion:Surgical pathological examination is more effective in gastric cancer examination,while live tissue examination under gastroscopy is less invasive,it is of great significance for the active prevention and effective treatment of gastric cancer lesions,and can be used as a primary diagnostic method for preoperative detection of gastric cancer.

关 键 词：胃癌 病理检查 弥漫浸润性病变 

分 类 号：R735.2[医药卫生—肿瘤]