中西医结合卒中单元模式对脑梗死恢复期患者的影响  

Influence of Stroke Unit Model of Integrated Chinese and Western Medicine on Convalescent Patients with Cerebral Infarction

作　　者：吴潇韩 周霞 郝琳瑶 李刘英[1,2] 罗彪 Wu Xiaohan;Zhou Xia;Hao Linyao;Li Liuying;Luo Biao(Department of Integrated Traditional Chinese and Western Medicine,Zigong First People's Hospital,Zigong 643000,China;Chengdu University of Traditional Chinese Medlcine,Chengdu 611137,China)

机构地区：[1]自贡市第一人民医院中西医结合科,自贡643000 [2]成都中医药大学,成都611137

出　　处：《成都医学院学报》2023年第6期701-704,710,共5页Journal of Chengdu Medical College

基　　金：四川省科技厅重点研发计划(No:2022YFS0392);2022年度发育与再生四川省重点实验室开放基金计划项目(No:SYS22-09);自贡市科技局重点科技计划项目(No:2021ZCYKY10)。

摘　　要：目的探讨中西医结合卒中单元模式在脑梗死恢复期患者中的临床疗效。方法选取2022年1—12月于自贡市第一人民医院住院的脑梗死恢复期患者160例为研究对象,按照随机数字表法分为对照组和试验组,每组80例。对照组按照西医卒中单元模式进行治疗,试验组在对照组治疗基础上采用中西医结合卒中单元模式。比较两组治疗前后中医证候积分及美国国立卫生研究院卒中量表(NIHSS)、汉密顿抑郁量表(HAMD)、日常生活能力(Barthel指数)评分。结果治疗4周后,两组中医证候积分、NIHSS评分、HAMD评分均较治疗前降低,且试验组分值均低于对照组(P<0.05);Barthel指数评分较治疗前升高,且试验组评分高于对照组(P<0.05)。试验组中医临床疗效、西医临床疗效均优于对照组(P<0.05);试验组中医临床和西医临床治疗总有效率均高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论中西医结合卒中单元模式可改善脑梗死恢复期患者的临床症状和神经功能,降低卒中后抑郁的发生率,并提高患者日常生活能力。Objective To investigate the clinical efficacy of an integrated Chinese and Western medicine stroke unit model on convalescent patients with cerebral infarction.Methods A total of 160 recovery-stage patients with cerebral infarction hospitalized in Zigong First People's Hospital from January to December 2022 were selected as the study objects.They were randomly assigned into either a control group(n=80)or an experimental group(n=80).The control group was managed according to stroke unit model of sole Western medicine,while the experimental group was managed according to stroke unit model of integrated Chinese and Western medicine in addition to Western medicine.The scores of TCM syndrome,National Institute of Health Stroke Scale(NIHSS),Hamilton Depression Scale(HAMD)and activity of daily living(Barthel index)before and after treatment were compared between the two groups.Results Following 4 weeks of treatment,both groups exhibited lower TCM syndrome scores,NIHSS scores,and HAMD scores compared to their respective pre-treatment values,and the above scores in the experimental group were lower than those in the control group(P<0.05).Additionally,Barthel index score post-treatment in both groups increased compared with that before treatment,and it was higher in the experimental group than it was in the control group(P<0.05).Notably,the experimental group demonstrated superior outcomes compared to the control group in terms of TCM clinical efficacy and clinical efficacy of Western medicine(P<0.05).The total effective rate in the experimental group was higher than that in the control group,regardless of treatment of TCM or Western medicine(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The implementation of the integrated traditional Chinese and Western medicine stroke unit model can effectively alleviate clinical symptoms and improve neurological function of convalescent patients with cerebral infarction,while reducing the incidence of post-s

关 键 词：中西医结合卒中单元 脑梗死恢复期 中医证候 神经功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学]